Protein Info for ABID97_RS08550 in Variovorax sp. OAS795

Annotation: aconitate hydratase AcnA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 926 transmembrane" amino acids 581 to 592 (12 residues), see Phobius details TIGR01341: aconitate hydratase 1" amino acids 23 to 925 (903 residues), 1277.6 bits, see alignment E=0 PF00330: Aconitase" amino acids 78 to 589 (512 residues), 524.3 bits, see alignment E=3.4e-161 PF00694: Aconitase_C" amino acids 720 to 852 (133 residues), 125.9 bits, see alignment E=1.3e-40

Best Hits

Predicted SEED Role

"aconitate hydratase 1( EC:4.2.1.3 )"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (926 amino acids)

>ABID97_RS08550 aconitate hydratase AcnA (Variovorax sp. OAS795)
MAKAPAHAFASTLKTFKTASGKSGKYWSLKELARQYPTVDRLPVSIRIVLESVLRNCDGQ
KVSPKHVEELAHWAPNAERTDEIPFVVTRVVLQDFTGVPLLADLAAMRSVAAKLGKSPKT
IEPLVPVDLVVDHSVMVDYYGTPKALELNMKLEFQRNNERYQFMKWGMQAFDTFRVVPPG
FGIVHQVNLEYFARGVYKSSSDNADVPVYYPDSLVGTDSHTTMINGVGVVGWGVGGIEAE
AAMLGQPVYMLTPDVVGFELTGKLREGVTATDLVLFVTAILRAEKVVGKFVEFFGPGAAS
IAVPDRATIGNMAPEYGATMGFFPVDEMTVAYFEGTGRTKEEVELFESYYKAQGLFGMPA
PGDIDYTKIVKLDLGTVSPSLAGPKRPQDRIDLGHLSTKFSELFSKPNDANGFNQPAERL
KLRYPLTASGRGDDEEAAPPPPKAGSVTIGNGDVLIAAITSCTNTSNPSVMLAAGLLAKK
AVEAGLTVKPHVKTSLAPGSRIVTEYLEKAGLLPYLEKLGFYLAGYGCTTCIGNAGDLTP
EINDAIVKNDLVGAAVLSGNRNFEARIHPNLKANFLASPPLVVAFAIAGNVMVDLMTEPV
GKGKNGKNVYLGDIWPTPKEIDDNLRFAMNARSFRENYDKVKSDPGKFWSSIKGTAGQVY
DWPESTYIAEPPFFADFKMAPHASDAGFKGARIMALFGDSITTDHISPAGSIKESSPAGI
WLKAHGVPKADFNSYGSRRGNHDVMMRGTFANVRIKNLMIPPDVNGTQEEGGVTLFQPGN
QKMFIYDAAMKYMEEGVPTVVFGGEEYGTGSSRDWAAKGTQLLGIKAVVARSFERIHRAN
LVGMGVLPLQFRGADSWQTLGLKGDEKIDVVIGGQLKPQMDVKLVVHRADGSHQEVTVRL
RIDTPIEVDYYKHGGILPFVLRQLLA