Protein Info for ABID97_RS08500 in Variovorax sp. OAS795

Annotation: succinate dehydrogenase, hydrophobic membrane anchor protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 121 transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 54 to 79 (26 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details PF01127: Sdh_cyt" amino acids 11 to 109 (99 residues), 45.7 bits, see alignment E=3.4e-16 TIGR02968: succinate dehydrogenase, hydrophobic membrane anchor protein" amino acids 14 to 119 (106 residues), 109.9 bits, see alignment E=3.3e-36

Best Hits

Swiss-Prot: 40% identical to DHSD_COXBU: Succinate dehydrogenase hydrophobic membrane anchor subunit (sdhD) from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

KEGG orthology group: K00242, succinate dehydrogenase hydrophobic membrane anchor protein (inferred from 98% identity to vap:Vapar_1429)

Predicted SEED Role

"Succinate dehydrogenase hydrophobic membrane anchor protein" in subsystem Succinate dehydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (121 amino acids)

>ABID97_RS08500 succinate dehydrogenase, hydrophobic membrane anchor protein (Variovorax sp. OAS795)
MSVNYGAKRIVVGAHYGLRDWLSQRITGGLMALFTIILLAQLIFTRGPIGYDLWAGIFAA
QWMKVLTFSVIVSLLYHVWVGMRDVWMDYVQPVGIRLALQIFTIVWLVGCAGWAIQVLWK
I