Protein Info for ABID97_RS07260 in Variovorax sp. OAS795

Annotation: TIM44-like domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 75 to 92 (18 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details PF04280: Tim44" amino acids 206 to 339 (134 residues), 83 bits, see alignment E=1.2e-27

Best Hits

KEGG orthology group: None (inferred from 91% identity to vap:Vapar_4128)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (341 amino acids)

>ABID97_RS07260 TIM44-like domain-containing protein (Variovorax sp. OAS795)
MKSLSSLFLACVLALVSVQADAARIGGGKSVGRQSSNVTQRESASPTAPTQQSATNAAPR
PATPAPAAAAPKRPWGAMLGGLAAGLGLAWLANSLGLGAGFANILLIGLLVMAALFAWRL
FKARSAASSGANRPGGFAFEGAGNPANASSPAQYSPNNVGNDASARPWERNASAFEATPA
PADERHGSSLSAAGAAAGGSMIGSALSGSQSWGIPVGFDVDGFLAAAKRNFVTLQDAWDR
ADVSTLRSMMTDGMVDEIRAQLADRASHTGGASNKTEVVMLDAKLLGIEELADVYMASVE
FSGMIREDASAGPGPFREVWNMTKPTSGNSGWLVAGVQALQ