Protein Info for ABID97_RS07170 in Variovorax sp. OAS795

Annotation: hemolysin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 134 to 157 (24 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details PF01595: CNNM" amino acids 8 to 197 (190 residues), 146.3 bits, see alignment E=1.2e-46 PF00571: CBS" amino acids 288 to 334 (47 residues), 19.1 bits, see alignment 2.1e-07 PF03471: CorC_HlyC" amino acids 349 to 426 (78 residues), 81.9 bits, see alignment E=3.9e-27

Best Hits

Swiss-Prot: 54% identical to YTFL_ECOLI: UPF0053 inner membrane protein YtfL (ytfL) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to vap:Vapar_4210)

Predicted SEED Role

"Putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>ABID97_RS07170 hemolysin family protein (Variovorax sp. OAS795)
MTLTQSLLIIVLLIAMSAFFSIAEITLAASRRLRLRQMADDGDARAEKVLRVQEQPGHYF
TVVQIGLNAVAILGGVVGEGSLSPYFARFFEHWMSVEASGNLAFLCSFVIVIAVFLVFAD
LFPKRLGMSNPERIAVRMVGPMLLLITAFKPLVWLFTRSTDMLFKLLGMPLVRDDKITSA
DILAMTEAGALAGVLAVREQQVIANVFELDTRLVSSVMTVRDNIAWFLHDDPESVLRARI
MAEPFSAYPVCDGDIDHVLGYVDAKEMFQRVLGGQPLAFDQGLTLHKALVIPDRLSLTEV
LEQFQQAREDFAIIVNEYSLVVGVITLNDVMSTVMGDLVSTPDEEQIVKRDENSWLIDGI
TPIQDVQRALHIDELPHPDEYETLAGFLMVMLRRVPKRTDSVSWGGYTFEVMDVDSYRID
QVMVTKT