Protein Info for ABID97_RS06780 in Variovorax sp. OAS795

Annotation: aldose epimerase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01263: Aldose_epim
  • amino acids 29 to 356 (328 residues), 286.6 bits, E=1.3e-89

Best Hits

Swiss-Prot: 42% identical to GALM_ACICA: Aldose 1-epimerase (mro) from Acinetobacter calcoaceticus

KEGG orthology group: K01785, aldose 1-epimerase [EC: 5.1.3.3] (inferred from 85% identity to vap:Vapar_1039)

MetaCyc: 42% identical to mutarotase (Acinetobacter calcoaceticus)
Aldose 1-epimerase. [EC: 5.1.3.3]

Predicted SEED Role

"Aldose 1-epimerase (EC 5.1.3.3)" in subsystem Lactose and Galactose Uptake and Utilization or Maltose and Maltodextrin Utilization (EC 5.1.3.3)

MetaCyc Pathways

• trehalose degradation VI (periplasmic) (1/2 steps found)
• D-galactose degradation I (Leloir pathway) (3/5 steps found)

KEGG Metabolic Maps

• Glycolysis / Gluconeogenesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.3

Protein Sequence (362 amino acids)

>ABID97_RS06780 aldose epimerase family protein (Variovorax sp. OAS795)
MPLPNSSTSARITTEAFGRMPDGRAVTEYTLDNGRGLRLSAINLGGIVTALQVPDRHGQG
GNVVLGLPSLEDYLKPHPHFGTIVGRYANRIAGGRFTLDGVAHQLPLNNGANSLHGGHQG
FGTRYWQIDAVPAQGDGDEVAIELRYTSADGEEGYPGEVQVTVRYALSTTENAWRIDYRA
VSDRATVLNLSHHDYFNLAGGGAVRDHRLMIPASRYCPVDAGLIPLGLATVAGTPFDFRE
PTLIGERIDDPHEQLRVAGGYDHNWVLDREPAGMALAARLAHAPSGRVMEVHTTEPAVQF
YSGNFLDGSLRGREGESFRQGAGLCLETQHYPDSPNQPEFPSTVLRPGDVFKSTTLHRFG
MC