Protein Info for ABID97_RS06415 in Variovorax sp. OAS795

Annotation: sigma-54 dependent transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 515 PF00072: Response_reg" amino acids 7 to 116 (110 residues), 97.5 bits, see alignment E=1.4e-31 PF00158: Sigma54_activat" amino acids 159 to 325 (167 residues), 230 bits, see alignment E=3.4e-72 PF14532: Sigma54_activ_2" amino acids 160 to 330 (171 residues), 85.5 bits, see alignment E=1e-27 PF07728: AAA_5" amino acids 182 to 296 (115 residues), 25 bits, see alignment E=4.1e-09 PF02954: HTH_8" amino acids 458 to 497 (40 residues), 42.2 bits, see alignment 1.3e-14

Best Hits

KEGG orthology group: K02667, two-component system, NtrC family, response regulator PilR (inferred from 89% identity to vap:Vapar_0958)

Predicted SEED Role

"Sigma-54 dependent transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (515 amino acids)

>ABID97_RS06415 sigma-54 dependent transcriptional regulator (Variovorax sp. OAS795)
MQRPANILVIDDEPDLRTLYELTLLREGYRVEAAGSVSEAWQHLEAGQFDAVITDMRLPD
GQGMEIIHRIQKNQRSERCVVMTAYGSAENAVEALKAGAFDYLTKPVDLKQFRAVVASAV
QARQAPPARAVRAAAAEPGEPRADALAVPASGITALQRLVGDSEPMRLVKSRIAKVARGM
APVLVRGESGTGKELVARAVHACSQRSEGPFVAVNCGAIPENLLEAEFFGARKGSYTGSS
QDRDGYFQAARGGTLFLDEIGDLPLAMQSKLLRAIQERSVRSIGSTQEDAVDVRVVSATH
KDLHAEVQAGRFRQDLFYRLNVIEIAVPALRDRREDLPALCAALLARIAQDGGLPVPHLS
VELLRRLAQHPLDGNVRELENLLHRAVALNDGDELHLDLTAGGRPGAAPPDAAAAATAPS
PLSSSVADGESPAAPAPSATAVADAKPAALPSDLQAYLDQQEREILVRALRESGFNRTAA
AARLGMSLRQIRYRIARLGITTPNGDEGAASPADD