Protein Info for ABID97_RS05500 in Variovorax sp. OAS795

Annotation: phospholipase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF02253: PLA1" amino acids 115 to 385 (271 residues), 288.2 bits, see alignment E=3.3e-90

Best Hits

KEGG orthology group: K01058, phospholipase A1 [EC: 3.1.1.32] (inferred from 90% identity to vap:Vapar_0719)

Predicted SEED Role

"Phospholipase A1 precursor (EC 3.1.1.32, EC 3.1.1.4); Outer membrane phospholipase A"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.32

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (388 amino acids)

>ABID97_RS05500 phospholipase A (Variovorax sp. OAS795)
MNPIQLRTTLAASLLLAPGLFAGPAQAQAVDKPRSPLAEAQLTWQQCAALGTNSEARLAC
FDRWAQQQTLPSVSVPVAPPVLASTQPPVDASIPATRVVSVATSEGCRDRQYSALSRFWE
LENGTDCGTFTFRGYRPLNVSASAATSKPDTPTSPSEGHTATPTSYQANEMRIGLSVRTK
IAQGLLTQNDPARKDSLWFAYSQQSTWQLFNGAISRPFRTTDHEPELIYVYPLDFNLPGG
WRWRYAGVGLVHQSNGQSLPLSRSWNRVYLMGGAELDDRFSITGRVWQRLSEDPAKDDNP
DISSYIGRAEVTGRWNFNRDNTLGVTVRNNLRDSGRGSIRLEWLKAIGDATTSNLRFHTQ
LFHGYGDTLVDYNRKRTVLSIGLSLVDF