Protein Info for ABID97_RS04535 in Variovorax sp. OAS795

Annotation: glycogen synthase GlgA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 1 to 487 (487 residues), 519.6 bits, see alignment E=3.7e-160 PF08323: Glyco_transf_5" amino acids 2 to 244 (243 residues), 251.3 bits, see alignment E=1.7e-78 PF13439: Glyco_transf_4" amino acids 104 to 232 (129 residues), 30.4 bits, see alignment E=5.7e-11 PF00534: Glycos_transf_1" amino acids 300 to 454 (155 residues), 30.7 bits, see alignment E=3.3e-11

Best Hits

Swiss-Prot: 88% identical to GLGA_VARPS: Glycogen synthase (glgA) from Variovorax paradoxus (strain S110)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 88% identity to vap:Vapar_0412)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.21

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (494 amino acids)

>ABID97_RS04535 glycogen synthase GlgA (Variovorax sp. OAS795)
MRILQVSAELFPLLKTGGLADVAGALPIALMAAGQDARVLLPGFPAILAGLGEAVPVAEF
AAPWGERFALRAGRIAIDGNPPLLAYVIDAPALYDRPGNPYEDAATRQPYTDNHRRFALL
GWAAAQLAQGLDPSWRPEVVHAHDWHAGLAPAYLHFARQAGAPRVGSVFTVHNLAYQGVF
PPWNFVDLGLPAPAFHMDGLEYHGQLSFMKGGLSYADRLTTVSPTYAREIQTPEQGFGLD
GLLRLRGGVLTGILNAVDDKVWNPASDAALMQGFHTPEGRHMAGKARCKSVLQHQLGLAE
RPDAPLFILVSRLTEQKGLHLVLGGLDALIAQGGQLALLGSGDTWLEDAFRERAAAAPQS
VSVTIGYNETLAHQLFGGGDVTLVPSLFEPCGLTQMYGLKYGSLPLVRRVGGLADTVVDC
TLEDMASGDATGFVFDRFDDADYGRALRRAFALYQHPPDWRRVRGTAMRRSADWATAADR
YIEVYRQALAPAGT