Protein Info for ABID97_RS04440 in Variovorax sp. OAS795

Annotation: NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 475 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 35 to 54 (20 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 134 to 157 (24 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 202 to 223 (22 residues), see Phobius details amino acids 242 to 271 (30 residues), see Phobius details PF02233: PNTB" amino acids 7 to 471 (465 residues), 621.2 bits, see alignment E=6.4e-191

Best Hits

Swiss-Prot: 60% identical to PNTB_RHORT: NAD(P) transhydrogenase subunit beta (pntB) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K00325, NAD(P) transhydrogenase subunit beta [EC: 1.6.1.2] (inferred from 98% identity to vap:Vapar_6042)

Predicted SEED Role

"NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)" in subsystem Phosphate metabolism (EC 1.6.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.1.2

Use Curated BLAST to search for 1.6.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (475 amino acids)

>ABID97_RS04440 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta (Variovorax sp. OAS795)
MSMNVVTLLYLVASVCFIQALKGLSHPTTSIRGNLFGMVGMAIAVVTTGALIYNLSGGHL
MGLGWVLLGLVAGGGYGAYRAKTVEMTKMPELVAFFHSMIGLAAVFIAVAAVVEPAAMLE
GIAKGAPIPAGNRLELFLGAAIGAITFSGSVIAFGKLSGTYKFRLFQGAPVQFKGQHMLN
LVLGLAMIGLGLVFMATESWPAFFAMLALAFVMGVLIIIPIGGADMPVVVSMLNSYSGWA
AAGIGFSLNNAMLIVAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGGEAVTAAGGAKE
QRPVKSGSADDAAFVLGNAETVVIVPGYGLAVARAQHAVKELAQKLTEKGITVKYAIHPV
AGRMPGHMNVLLAEAEVPYDQVFEMEDINGEFGQADVAIILGANDVVNPAALTKGSPIYG
MPILEAYKAKTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVVEDMGKAIE