Protein Info for ABID97_RS03560 in Variovorax sp. OAS795

Annotation: molybdopterin cofactor-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1253 transmembrane" amino acids 823 to 845 (23 residues), see Phobius details PF20256: MoCoBD_2" amino acids 47 to 172 (126 residues), 73 bits, see alignment E=6.1e-24 amino acids 615 to 684 (70 residues), 55.3 bits, see alignment 1.5e-18 PF02738: MoCoBD_1" amino acids 318 to 558 (241 residues), 110.7 bits, see alignment E=1.3e-35 PF00034: Cytochrom_C" amino acids 864 to 964 (101 residues), 28 bits, see alignment E=8.8e-10 PF13442: Cytochrome_CBB3" amino acids 1145 to 1223 (79 residues), 33.3 bits, see alignment 9.8e-12

Best Hits

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1253 amino acids)

>ABID97_RS03560 molybdopterin cofactor-binding domain-containing protein (Variovorax sp. OAS795)
MTRRADLPRTRADFLSADGVLLVVRETPPAPPPAKGQPTAVAGNPAEGDEILLAVWDDGS
ASALNGHVDLGTGIQTALAQIVAEELDLGMPCVRMMLGDTARAPNQGATIASASIQIHSQ
PLRLAAAQARAWLLARAADRLGVAVQALQVRNGVVRLAEEPDRRIDYADLVAGQRTVLRL
DPHAQPKAPADYRIVGTRQARVDIPAKLAGESVFVHDMRVPGMLHGRVVRPPYAGADHGE
FIGNTLDAVDESSIAHIPGIRAVVVVRDFVGIVAEREEHAEQALRELRVTWKPWPGMPDL
SDLAQALRDNPSTQRLLVDEGDVDGALAAAAQPMHRTYVWPYQMHASIGPSCALADWQPR
DGSGMQLRVWAGSQNPHVLRADLAKLMGVDDVQVDVVRMEAAGCYGRNGADDVAADAALL
ARAVGAPVRVQLTREQEHAWEPKGAAQLMEVDGGLMADGRIAAYDFETSYPSNGAPTLAL
LLTRTIEPVAQAFEMGDRTARPPYSVDNLRVKVNDMAPIVRASWLRGVSALPSSFAHESY
IDELATAAGVDPVQFRLRHLNDPRAVELVQATAQKAGWRMRTGPQENADGGLGEGGDILF
GQGFAYARYIHSKWPGFGAAWAAWVADVEVNRKTGEVHVRRVVVGHDAGLMINPAGVEHQ
VHGNVIQTTSRALKEEVRFAPQQGAANGGPQLPGVLPSGVVASREWGSYPIINFREVPVV
EIMHMPRPGEPSLGAGESSSVPGTAAIANAIFDATGVRFREPPFTAEKVLAALRPLTSDL
PPLPPGEGWGEGERPANRDAVAPSSQPSPRGRRSNTAWPQRKGLLATGAALFIGGIGLIA
GLLGWRSAIAPVSLSAPVYSQATVERGRVLAALGDCAVCHTAAGGAPNAGGRAMETPFGT
LYTTNLTPDADTGLGRWSFSAFQRAMREGVSRDGHHLYPAFPYTAFAKTSDDDLQALYAY
FMSMPAVRAETPKAELKFPFSMRPLMAGWNALFHDPAPLQPVAAQNAEWNRGAYLVNGLG
HCGACHTPRNALGAEQGGSAFLSGAMVEGWEAPALTGLSKSAVPWDADELYRYLRQGHTR
RHGIAGGPMAEVVRELAEVPDADVRAMATYLASFDPAPAAQPQAVAQQAVDTAARTQGQL
LGPAQRMFDSACASCHHDGDGPTLLGVNTPLALNSNLTSARPDNLLRTILDGVREPASRG
IGFMPAFREALDDRQVAELAGYMRARFAPQEPAWKNLPAEVARVRAARGHGAP