Protein Info for ABID97_RS03445 in Variovorax sp. OAS795

Annotation: N-formylglutamate deformylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02017: N-formylglutamate deformylase
  • amino acids 11 to 268 (258 residues), 345.5 bits, E=1e-107
• PF05013: FGase
  • amino acids 18 to 237 (220 residues), 256.5 bits, E=1.6e-80

Best Hits

KEGG orthology group: K01458, N-formylglutamate deformylase [EC: 3.5.1.68] (inferred from 89% identity to vap:Vapar_0166)

MetaCyc: 53% identical to N-formylglutamate amidohydrolase (Pseudomonas putida)
N-formylglutamate deformylase. [EC: 3.5.1.68]

Predicted SEED Role

"N-formylglutamate deformylase (EC 3.5.1.68)" in subsystem Histidine Degradation (EC 3.5.1.68)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Histidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.68

Use Curated BLAST to search for 3.5.1.68

Protein Sequence (271 amino acids)

>ABID97_RS03445 N-formylglutamate deformylase (Variovorax sp. OAS795)
MRFITTEPPFRFRRGTRPLLISMPHVGTHVPPALAARFTEEARQVPDTDWHLERLYGFAD
ALGASVLVATHSRYVIDLNRPPDGASLYPGQSVTGLCPVDTFDDTPVYASADDLPGDEEI
AARRDAIWRPYHQQLEAELGRLKAAHGTVALWDAHSIRSVLPRFFEGKLPDLNLGTANGA
SCDAGLAATLLGIAESAPGYTGVLNGRFKGGHITRQYGNPAAGVHAVQLEMTQSSYMQEQ
LPFDYLPDVAAGVQPHVQRMIEAVLAFVEGR