Protein Info for ABID97_RS03325 in Variovorax sp. OAS795

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF00106: adh_short" amino acids 10 to 200 (191 residues), 135.8 bits, see alignment E=2e-43 PF08659: KR" amino acids 12 to 113 (102 residues), 36.2 bits, see alignment E=8.6e-13 PF13561: adh_short_C2" amino acids 19 to 250 (232 residues), 152.9 bits, see alignment E=1.7e-48

Best Hits

Swiss-Prot: 40% identical to DECR_HUMAN: 2,4-dienoyl-CoA reductase, mitochondrial (DECR1) from Homo sapiens

KEGG orthology group: None (inferred from 59% identity to hne:HNE_0595)

Predicted SEED Role

"hypothetical oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (306 amino acids)

>ABID97_RS03325 SDR family oxidoreductase (Variovorax sp. OAS795)
MFEANLLRGKRILVTGGGSGLGREIAERYLQLGAEVHICGRRQPMLDATAAELTERHGGV
VRAHAVDIRHADAVDAMVGRIWAEHGPLDGLVNNAAGNFVSRTQDVSPRGFDAVANIVLH
GTYYVTHHVGRRWIETGHKGSVISIVVTWVRTGAPFVVPSAMSKAGVDVMTKSLAIEWGR
YGIRLNAIAPGIFPTEGANSRLSPKAAWEDGAVRNPMNRLGRMPELQNLAVFLMADGVEW
ITGETIAIDGAGHRQNGASFTELADLDEEAWRGMREAIRGQDARDRALRAEVSEPAAADD
APRGRS