Protein Info for ABID97_RS02550 in Variovorax sp. OAS795

Annotation: M20/M25/M40 family metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 430 to 445 (16 residues), see Phobius details PF04389: Peptidase_M28" amino acids 115 to 208 (94 residues), 34.2 bits, see alignment E=4.5e-12 PF01546: Peptidase_M20" amino acids 130 to 426 (297 residues), 65.7 bits, see alignment E=1.2e-21 PF07687: M20_dimer" amino acids 237 to 336 (100 residues), 54.3 bits, see alignment E=2.3e-18

Best Hits

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_5278)

Predicted SEED Role

"peptidase M20"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>ABID97_RS02550 M20/M25/M40 family metallo-hydrolase (Variovorax sp. OAS795)
MLRSPRALRLAPLSALVLAMFCAVQVAQAQNAAVAPTPAQVAPEVDKAFMQLMAAPAVQK
LLDAVKADHERSVEDLKMLTEIEAPPFKEQKRAEAFLARMKALGLADAKIDAEGNVVGLR
KGTGNGPKLLISAHLDTVFPAGTDVKVKEHDGKLHAPGIADDTRGLSVLLSWLKVLNDNK
VQTVGDLLFVANVGEEELGNLRGMKAIFRDHLDIDGMVGLEPSPDGNVLILGTASHRYEV
TFKGPGGHSFAAFGQVPSAIHGMGRAIAKIAEVRTPSFPKTTFTVGTVGGGTSVNTIAPD
ARMAVDIRSDDMASLLETEKKILAAIDEAVAEENKRWNVGTLSASHKLIGDRPGGRTPSD
SVMVEAAIRANTAFGHKTLLRGGSTDANVPMSYGIPAVIVGGGGKSTGFHALSESIDVTD
AWKGAQNSLVTVLGLVGVQGVSPALLPKRPARTR