Protein Info for ABID97_RS02360 in Variovorax sp. OAS795

Annotation: M20 aminoacylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 TIGR01891: amidohydrolase" amino acids 15 to 385 (371 residues), 350.2 bits, see alignment E=7.1e-109 PF01546: Peptidase_M20" amino acids 73 to 394 (322 residues), 142.5 bits, see alignment E=1.7e-45 PF07687: M20_dimer" amino acids 187 to 280 (94 residues), 34.3 bits, see alignment E=2e-12

Best Hits

Swiss-Prot: 42% identical to HIPO_CAMJE: Hippurate hydrolase (hipO) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

KEGG orthology group: None (inferred from 96% identity to vap:Vapar_5224)

Predicted SEED Role

"Metal-dependent amidase/aminoacylase/carboxypeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>ABID97_RS02360 M20 aminoacylase family protein (Variovorax sp. OAS795)
MNIVDSFANNAARFVDIRRDIHAHPELGFEEHRTSEKVAGLLAEWGIEVHRGIAGTGLVG
VLRKGTGSRTIGLRADMDALPMQEANEFAHKSTHAGRMHACGHDGHTTMLLAAAWHLSRQ
GPDDFDGTVHFIFQPAEEMGKAGAKKMIQDGLFERFPCDAVFALHNFPVGDVGRFALNEG
ALMASSNTYKVTLRGRGTHASMPHTGIDPVAAVVTLAQQLQTIVPRTIPSTERALLAVTQ
LQGSDAPNVIPDVATVGGTIRTFSIEAIDKIEARLREVAAGVAAAHGCTAEVFFNRSSPP
VVNHVAEARFAAGVMREVVGDGMVTDDFPAVMGAEDFAHMLLARPGCYAFLGNGDGDHRL
GGHGPGPCIIHNTSFDFNDEIIPIGASYFVKLVQRWLPSGS