Protein Info for ABID97_RS01720 in Variovorax sp. OAS795

Annotation: HipA domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 PF13657: Couple_hipA" amino acids 11 to 116 (106 residues), 63.3 bits, see alignment E=2.6e-21 TIGR03071: HipA N-terminal domain" amino acids 13 to 116 (104 residues), 44.7 bits, see alignment E=5.8e-16 PF07804: HipA_C" amino acids 156 to 397 (242 residues), 133.9 bits, see alignment E=6.7e-43

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 91% identity to vpe:Varpa_5814)

Predicted SEED Role

"Possible HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>ABID97_RS01720 HipA domain-containing protein (Variovorax sp. OAS795)
MYLHAPGGGRRAIGHLSQYGDILRVSFDEAYMADPARPTLSLAYRGADEAATRAILASAR
DARVSRGDGHWPSYFQNLLPEGHNRERLAQQRGCSADDEFELLAAAGHDLMGALEVEPVP
AAEGIPDTVRHWHTALGLDVLEPGFVELPVEDAAAIPGVVTKFSAVQDGRRYVVRRHGAA
GSFILKLPTTRHPDLVANEHTGYRLCGALGLDCAEASVIERSEADLPEQVPFGQILAVRR
FDRTAGGGRIHMEEFAQVLQYEPRQKYGRGLNVDWPAMLRVLDRLSPNPVADVRECVRRI
VAFILLGNSDAHLKNWALRYPDGIAPVLAPLYDPVCVAAFFEDVPSTDYAVNRAIDARLR
AFDWPALEALLRAAGLLRPGRLMAIARDTVRQAQAAWPALLDDAATPASVRHCVRARLAG
GTALAG