Protein Info for ABID97_RS01425 in Variovorax sp. OAS795

Annotation: bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 795 PF05834: Lycopene_cycl" amino acids 19 to 165 (147 residues), 24.6 bits, see alignment E=2e-09 PF00724: Oxidored_FMN" amino acids 417 to 744 (328 residues), 209.3 bits, see alignment E=1.5e-65

Best Hits

KEGG orthology group: K09461, anthraniloyl-CoA monooxygenase [EC: 1.14.13.40] (inferred from 96% identity to vap:Vapar_5038)

MetaCyc: 64% identical to 2-aminobenzoyl-CoA monooxygenase/reductase subunit (Aromatoleum evansii)
Anthraniloyl-CoA monooxygenase. [EC: 1.14.13.40]

Predicted SEED Role

"Anthraniloyl-CoA monooxygenase (EC 1.14.13.40)" (EC 1.14.13.40)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (795 amino acids)

>ABID97_RS01425 bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase (Variovorax sp. OAS795)
MNSLNAGLSAAPAMDLQRILCIGGGPAGLYFALLMKARNPALEITVVERNRPFDTFGWGV
VLSDQTLANLAAADADTAALIGNEFHHWDDIQVFFKGRQVRSGGHGFCGIGRKRLLNILQ
ERCLELGVKLVFETDATDDQAIAAEYNADLVIASDGLNSRIRQRYADVFKPDIDLRNCRF
VWLGTHQTFDAFTFAFEQTEHGWFQAHAYQFDDKTSTFIVETPEEVWKAHGLDQMEQPEA
IAFCEKLFARYLGGHPLISNATHLRGSANWIRFPRVVCERWTHRIDVEGRSVPVVLMGDA
AHTAHFSIGSGTKLALEDAIDLANEFERGGTVDHVLEGYEARRSVEVLKIQNAARNSTEW
FENVPRYTGMQIEQFAYSLLTRSQRISHENLRVRDTEWLGGYERWLAGGKPVAPMLMPLT
VRGVTLKNRILVSPMATYSAVDGVPQDFLLVHLGARALGGAAMVCVEMTSPTPEGRITPG
CTGLYNDAQQAAFKRIVDFVHTQSSAKIAMQLGHSGAKGSTRVGWEGTDEPLESGNWPLL
SASPVAYGEQNQLPAAMTREQMDDMRERFVDATRRTAECGFDWLELHCAHGYLLSSFISP
LTNLRTDEYGGGIEARCRYPLEVFRAMRAVWPADKPMSVRISAHDWAPGGNTDADAVIVA
RLFKEAGADFIDVSSGQTTRAAKPVYGRMYQTPFSDRIRNEVGISTIAVGAITDADQANS
IIAAGRADLCAIARPHLADPAWTLHEAAKLQSRDVDWPKQYLSGRDQLYREIAKQQQMAA
AANAALAAQNPEETH