Protein Info for ABID97_RS01285 in Variovorax sp. OAS795

Annotation: fumarylacetoacetate hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 PF01557: FAA_hydrolase" amino acids 78 to 290 (213 residues), 222.7 bits, see alignment E=2.3e-70

Best Hits

KEGG orthology group: None (inferred from 68% identity to vap:Vapar_0616)

Predicted SEED Role

"Fumarylacetoacetate hydrolase family protein" in subsystem Gentisare degradation or Salicylate and gentisate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>ABID97_RS01285 fumarylacetoacetate hydrolase family protein (Variovorax sp. OAS795)
MKLGTVELRTGEERLACLRADGNAVLAPREFGDMQRVIEACDLAVPALRKLCESAQSEGI
ALSELRLLSPVRRLRRDVLCTGWNYWDHFHESEGKREGQDVPKPEAPTFFTKGPDVLIGP
HDDIAFDPAISSKWDYEAEIALVIGKEGRSIPREHAMAHVFGYCLANDISQRDLQRRHGG
QWLKGKSIDGTMPLGPWLTLRDDAELPAITLECELNGAVMQQASASQMAFGIAELVSELS
FGMTLKPGDVLLTGTPSGIGNARTPPVFLKEGDLVVVRATGLGELRNRLVAKDLSSYATP
A