Protein Info for ABID97_RS01150 in Variovorax sp. OAS795

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 PF26965: MimR_N" amino acids 21 to 201 (181 residues), 53.4 bits, see alignment E=6.7e-18 PF01590: GAF" amino acids 92 to 220 (129 residues), 26 bits, see alignment E=2.9e-09 PF02954: HTH_8" amino acids 368 to 408 (41 residues), 49.3 bits, see alignment 8.4e-17 PF13518: HTH_28" amino acids 381 to 412 (32 residues), 28 bits, see alignment (E = 4.6e-10)

Best Hits

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_5019)

Predicted SEED Role

"Sigma-54 activated regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>ABID97_RS01150 helix-turn-helix domain-containing protein (Variovorax sp. OAS795)
MAFERLGTATAPRQLFSTTPAQRVALARQQFFEEGVRPSGLVGEAVIQSWLRCTRNHSDR
QRIVPFDAVTPSRLHATLARNRELLEVARQELASMESALSGTDSRVILTDGEGVVVHVTQ
HPTGAHQPVLRKTARVGVNISERMVGTTAPGIVATTGQACTVDGAEHYFDVLSQMQCAAA
PIRDVTGRLAGVLDITMEARRFGFDAASMVALYATTIENRLLQSQSRDHLILRFQASPNL
LGTPMEALAGVAPDGTIAWLNSAGARLIGRLPEEACERDVESMLGHDLASLLRLERREAA
QPLRLASGLGVWVQARLKAADGADFRHAVAMPGESIAVAALTPAPIETVPPEKGAAKAQA
PEAPHGETLREHSRKLIEDALAMQGGNVSQAARQLGVSRGTLYRRLQDWRAEDKRRAAEE
A