Protein Info for ABID97_RS00750 in Variovorax sp. OAS795

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 PF00106: adh_short" amino acids 3 to 196 (194 residues), 161.5 bits, see alignment E=2.8e-51 PF08659: KR" amino acids 5 to 184 (180 residues), 54.1 bits, see alignment E=2.8e-18 PF13561: adh_short_C2" amino acids 12 to 247 (236 residues), 176.3 bits, see alignment E=1.2e-55

Best Hits

Swiss-Prot: 58% identical to YGFF_ECOLI: Uncharacterized oxidoreductase YgfF (ygfF) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to vap:Vapar_4932)

Predicted SEED Role

"Short chain dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (248 amino acids)

>ABID97_RS00750 SDR family oxidoreductase (Variovorax sp. OAS795)
MDQVLLITGGGRGIGAATALLAAQRGYAVAVNYASNSLAADEVVRTIRAGGGTAVAVQAD
VGDEAQVAAMFQKVDARLGRLTALVNNAGVVDVQARVDEMSVARLERMFRTNVIGSFICA
REAVRRMSTRYGGAGGAIVNISSAAARLGSPGQYVDYAASKGAIDTFTIGLAKEVAAEGI
RVNAVRPGLIDTEIHASGGMPDRAFELAPTVPMQRTGSADEIAGAILWLLSEEASYTTMA
LLDVTGGR