Protein Info for ABI39_RS21310 in Phocaeicola dorei CL03T12C01

Annotation: glycoside hydrolase family 2 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 855 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00703: Glyco_hydro_2" amino acids 216 to 326 (111 residues), 58.1 bits, see alignment E=2.1e-19 PF17786: Mannosidase_ig" amino acids 685 to 773 (89 residues), 66.7 bits, see alignment E=3.2e-22 PF17753: Ig_mannosidase" amino acids 776 to 854 (79 residues), 63.1 bits, see alignment E=2.3e-21

Best Hits

KEGG orthology group: K01192, beta-mannosidase [EC: 3.2.1.25] (inferred from 100% identity to bvu:BVU_4139)

Predicted SEED Role

"Beta-mannosidase (EC 3.2.1.25)" in subsystem Mannose Metabolism (EC 3.2.1.25)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.25

Use Curated BLAST to search for 3.2.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (855 amino acids)

>ABI39_RS21310 glycoside hydrolase family 2 protein (Phocaeicola dorei CL03T12C01)
MKKTLKVLMMLGCFPMMLSAKEYKKSESLSLDKGWEFAQVGRNEWLPATVPGTVHQDLIS
HNKLPNPFYGMNEQKVQWVENEDWVYKTTFNVTDEQLSRDAALLILEGLDTYADIYLNGS
LLERTDNMFVGYTLPVKEVLRKGENHLQILFHSPVKQTLPQWETNGFDYPADNDHSDKRV
SIYSRKAPYSYGWDWGIRLVTSGIWRPVTLTFYDVARIDDYYVRQASVTKDLAKVENLLT
VNSVSATPQKAEVTVAYSYKEGEKVTEQKEVTLQPGTNHILLPIEIRQPHLWMPNGWGEP
ALYDFEAVIKVDGKVIASQKERIGLRTIKVVKEKDDQGESFYFVVNGEPMFAKGANFIPD
DALLPNITEERYRQLFKDVKDANMNMIRVWGGGIYEDDVFYQAADENGILVWQDFIFACT
TYPSDPAFMKRVEAEAEYNIKRLRNHASLAMWCGNNEIYEGMRYWGWDKKYTDPGIMEGM
KQGYDKLFRELLPRKVAELDPDRFYMHGSPYEANWGRPESWKIADSHNWGIWYGQKPFES
LDTEIPRFMSEFGFQAFPEMKTIATFASPEDYALESEVMNAHQKATIGNFLIKKTMGLYY
KVPEDFDQLVYMGLVLQGVGVRQGLEAHRRNRPYCMGTLYWQLNDSWPVVSWSSIDYYGN
WKALHYQAKRAFAPVLVDAVKEGEDLNIYVMSDKLEADKEVTLLLRVMDFNGKVLTKKSI
KGEVPANASTLYYKEPYAGITTSPQNTFLLMTLKNKKGEVLSEEIYYFNHAKDQELPKTE
IRYKVKPMDGKYEVTLSARQLARDVFIEIPVQGAKFTDNFFDLLPGQTKKVIITSDKLKK
NEKVDITIKQLSDTN