Protein Info for ABI39_RS18655 in Phocaeicola dorei CL03T12C01

Annotation: alcohol dehydrogenase catalytic domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 transmembrane" amino acids 171 to 189 (19 residues), see Phobius details PF08240: ADH_N" amino acids 27 to 129 (103 residues), 94.3 bits, see alignment E=4.1e-31 PF13602: ADH_zinc_N_2" amino acids 225 to 333 (109 residues), 27.5 bits, see alignment E=5.5e-10

Best Hits

KEGG orthology group: None (inferred from 98% identity to bvu:BVU_3770)

Predicted SEED Role

"Threonine dehydrogenase and related Zn-dependent dehydrogenases" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (348 amino acids)

>ABI39_RS18655 alcohol dehydrogenase catalytic domain-containing protein (Phocaeicola dorei CL03T12C01)
MLAYTYIKQGKFELIEKPKPELRGSRDAIVRVTLGSICTSDLHIKHGGVPRAVPGITVGH
EMVGIVEQTGRDVKLVKPGDRVTVNVETFCGECFFCRHGYVNNCADPNGGWALGCRIDGG
QTEYVRVPYADQGLNLIPDSVSDEQALFVGDILATGFWAARISEITEEDTVLVIGAGSTG
ICTLLCVMLRKPQRIVVCEQSSERIRFVREHYPQVEVVTPEECKEFVLQSGPHGGADVVF
EVAGGEDTFRLAWECARPNAVVILVALYDRPQILPLPDMYGKNLIFKTGGVDGCDCAEIL
RLIEMGKIDTTPLITHRFPLDQIETAYQIFENRQDGVIKVAVAMEAGM