Protein Info for ABI39_RS17495 in Phocaeicola dorei CL03T12C01

Annotation: pyruvate, phosphate dikinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 908 TIGR01828: pyruvate, phosphate dikinase" amino acids 3 to 904 (902 residues), 1343.8 bits, see alignment E=0 PF01326: PPDK_N" amino acids 22 to 390 (369 residues), 246.4 bits, see alignment E=7.1e-77 PF00391: PEP-utilizers" amino acids 456 to 537 (82 residues), 75.3 bits, see alignment E=3.6e-25 PF02896: PEP-utilizers_C" amino acids 553 to 903 (351 residues), 264.6 bits, see alignment E=1.5e-82

Best Hits

KEGG orthology group: K01006, pyruvate,orthophosphate dikinase [EC: 2.7.9.1] (inferred from 99% identity to bvu:BVU_3358)

Predicted SEED Role

"Pyruvate,phosphate dikinase (EC 2.7.9.1)" in subsystem Glycolysis and Gluconeogenesis or Glycolysis and Gluconeogenesis, including Archaeal enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 2.7.9.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.9.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (908 amino acids)

>ABI39_RS17495 pyruvate, phosphate dikinase (Phocaeicola dorei CL03T12C01)
MDKKRVYTFGNGQAEGKADMRNLLGGKGANLAEMNLIGVPVPPGFTITTEVCSEYYELGR
DKVVELLKADVEKAIANIESLMNSKFGDIENPLLVSVRSGARASMPGMMDTILNLGLNDE
VVEGLSRKTGRPRFAWDSYRRFVQMYGDVVLGMKPVNKEDIDPFEEIIEKVKEEKGVKLD
NELEVEDLKELVKRFKVAVKEQTGQDFPTCAYEQLWGAICAVFRSWMNERAILYRKMEGI
PAEWGTAVSVQAMVFGNMGDTSATGVCFSRDAGNGEDLFNGEYLINAQGEDVVAGIRTPQ
QITKIGSQRWAERAGISEEERIAKYPSMEEAMPEIYKELDALQTKLENHYRDMQDMEFTV
QEGKLWFLQTRNGKRTGAAMVKIAMDLLRQGMIDEKTALERCEPNKLDELLHPVFDKKAL
KEAKVLTRGLPASPGAATGQIVFFADDAAKWAADGKKVVMVRIETSPEDLAGMAVAEGIL
TARGGMTSHAAVVARGMGKCCVSGAGAINVDYKTRTVEIEGITLKEGDFISLNGTTGEVY
KGKVETKAAEVSGDFAALMDLCNKYTKLNVRTNADTPHDAEVARAFGASGIGLCRTEHMF
FDAEKIVAMREMILSPDVEGRRKALAKLLPYQKADFKGIFKAMDGCPVNVRLLDPPLHEF
VPHDAKGQEEMAKAMGVTVQEIKKRVESLCEHNPMLGHRGCRLGNTYPEITEMQTQAILG
AAIELKKEGYDPHPEIMVPLTGILYEFEAQEKVIRDAAAALFEKEGMEIPFKVGTMIEIP
RAALTANRIASRAEYFSFGTNDLTQMTFGYSRDDIASFLPVYLEKKILKVDPFQVLDQNG
VGQLIEMAVDKGRSVRPDLKCGICGEHGGEPSSVKFCHKVGLNYVSCSPFRVPIARLAAA
QAAVEDMK