Protein Info for ABI39_RS17475 in Phocaeicola dorei CL03T12C01

Annotation: membrane protein insertase YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 338 to 355 (18 residues), see Phobius details amino acids 364 to 387 (24 residues), see Phobius details amino acids 438 to 459 (22 residues), see Phobius details amino acids 486 to 506 (21 residues), see Phobius details amino acids 527 to 543 (17 residues), see Phobius details amino acids 549 to 565 (17 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 2 to 342 (341 residues), 80.3 bits, see alignment E=2.2e-26 PF14849: YidC_periplas" amino acids 84 to 351 (268 residues), 106.2 bits, see alignment E=3.1e-34 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 367 to 566 (200 residues), 169.6 bits, see alignment E=8.3e-54 PF02096: 60KD_IMP" amino acids 369 to 566 (198 residues), 165.5 bits, see alignment E=1.1e-52

Best Hits

Swiss-Prot: 99% identical to YIDC_BACV8: Membrane protein insertase YidC (yidC) from Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 99% identity to bvu:BVU_3354)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (622 amino acids)

>ABI39_RS17475 membrane protein insertase YidC (Phocaeicola dorei CL03T12C01)
MDKNTLVGFALIGAVVIGFSIYNRPSQEEMARAKHYQDSIQAIAQKEAERQAQVATTQSQ
NATLHLDSTSMFYGASQGAEQLTTLENNVVKLTFTNKGGRVCAAILKDYNGQDGKPLMLF
DEKDSGMNFAFEGKNENILTEDMYFQPTNVTDSTVTMRLAANNGGYIDFDYKLLPDAYMV
NFTIRANGMQNFFPPALNTVNINWRQRARQLEKGFSFEQRYTSLTYKPVEKSSDYLNEMK
EAKEDVTDRLDWIAFKNQFFSSVLIADQDFDKASLTSTPQQEGSGYMKNYTADMTTFFDP
TGKQSTNMQFYFGPNHFKTLLNSNDLSLSQKDLELEDLVYLGWPIIRWVNRWFTINLFDW
LSGWGLSMGVVLLLMTIIVKVLVYPATYKSYMSSAKMRVLKPYINEINAKYPKKEDALKK
QQETMALYSKYGVSPMGGCLPMLIQMPVFMALFFFVPNAIELRQQSFLWAPDLSTYDDII
NWGTNIPLLGNHLSLFCLLFSITNILNTMYTMKQQDMGQQQMPGMKLMMYIMPVMFIFIF
NGYSSGLNYYYFISGLIGILTMVILRKTTDEKKLLAMLEARKEKKSQKNGGKPGGGGLMA
KLEALQKEQERLQQERMNKGKK