Protein Info for ABI39_RS17050 in Phocaeicola dorei CL03T12C01

Annotation: potassium-transporting ATPase subunit KdpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 65 to 86 (22 residues), see Phobius details amino acids 129 to 154 (26 residues), see Phobius details amino acids 170 to 193 (24 residues), see Phobius details amino acids 251 to 276 (26 residues), see Phobius details amino acids 283 to 302 (20 residues), see Phobius details amino acids 374 to 400 (27 residues), see Phobius details amino acids 421 to 442 (22 residues), see Phobius details amino acids 490 to 517 (28 residues), see Phobius details amino acids 537 to 558 (22 residues), see Phobius details TIGR00680: K+-transporting ATPase, A subunit" amino acids 7 to 567 (561 residues), 624.1 bits, see alignment E=1.1e-191 PF03814: KdpA" amino acids 11 to 566 (556 residues), 748.8 bits, see alignment E=1.4e-229

Best Hits

Swiss-Prot: 99% identical to KDPA_BACV8: Potassium-transporting ATPase potassium-binding subunit (kdpA) from Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

KEGG orthology group: K01546, K+-transporting ATPase ATPase A chain [EC: 3.6.3.12] (inferred from 99% identity to bvu:BVU_3267)

Predicted SEED Role

"Potassium-transporting ATPase A chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (568 amino acids)

>ABI39_RS17050 potassium-transporting ATPase subunit KdpA (Phocaeicola dorei CL03T12C01)
MNTEVLGVIAQIVLLIVLSYPLGKYIAKVYKGEKTWSDFMKPVERVMFKLSGINPNEEMN
WKQFLRALLVVNLFWFLWGMVLLVTQGVLPLNPDGNAGQTAHQAFNTCISFMVNCNLQHY
SGESGLTYFTQLFVIMLFQFITAATGMAAMAGIMKALAAKTTQTIGNFWNYLVLSCTRVL
LPLSLIVGFILIVQGTPMGFDGKMKVTTMEGTTQYVSQGPTAAIVPIKQLGTNGGGYFGV
NSSHPLENPTYFANMVECWSILIIPMAMAFAFGFYLKRKKLGYSIYGVMLFAYLVGVCIN
VSQEMGGNPRIDEMGIAQDNGAMEGKEIRLGSAATALWSITTTVTSNGSVNGMHDSTMPL
SGMMEMLNMQINTWFGGVGVGWMNYFTFIIIAVFISGLMVGRTPEFLGHKVEAREMKIAS
IVALLHPFIILVGTALAAYLFVHAPAFVESEGGWLNNPGYHGLSEMLYEYTSCAANNGSG
FEGLGDNTWFWNYSCGIVLILGRFVPIVGQVAIAGILAKKKFIPESAGTLQTDTVTFGVM
TFAVIFIVAALSFFPVHALSTIAEHLSL