Protein Info for ABI39_RS16630 in Phocaeicola dorei CL03T12C01

Annotation: multidrug effflux MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 9 to 30 (22 residues), see Phobius details amino acids 45 to 65 (21 residues), see Phobius details amino acids 77 to 96 (20 residues), see Phobius details amino acids 102 to 123 (22 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 216 to 236 (21 residues), see Phobius details amino acids 247 to 270 (24 residues), see Phobius details amino acids 280 to 302 (23 residues), see Phobius details amino acids 308 to 327 (20 residues), see Phobius details amino acids 338 to 356 (19 residues), see Phobius details amino acids 362 to 383 (22 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 8 to 373 (366 residues), 254.4 bits, see alignment E=1.3e-79 PF00083: Sugar_tr" amino acids 15 to 187 (173 residues), 43.2 bits, see alignment E=3.9e-15 PF07690: MFS_1" amino acids 17 to 354 (338 residues), 151.2 bits, see alignment E=5.5e-48

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 78% identity to bfs:BF2930)

Predicted SEED Role

"Bicyclomycin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>ABI39_RS16630 multidrug effflux MFS transporter (Phocaeicola dorei CL03T12C01)
MKETLNSKLYILVVIGIVSAFGPFVTDFYLPALPVLAGYFDTTASLVQLSLTFSMVGLAV
GQLVIGPLSDKYGRKKTLMASLVLFCISTIGCLYASDIYVFIFFRLLQGLSGAGGVVISK
SIATDLYEGRELTRFFSMLSSVQGIAPVCAPVLGGVLLEVTDWKGIFWILVLIGILLIMA
LAFFKESLNNEQQHCGVFATFRNYIPVFQNAQFMRYVLVQAFAMGVMFTYIAASPFIFQE
HFNMSPLAYSLCFGANAIAIMLGSLTVSLFHDATDALRVGSIGFGIMSLFVAAALFFSTS
VWPVEVSLFVFMLFLGVILPSSTTLALDLERKNSGNASALLGFLMFLFGGVLSPLTGLGN
MLYTTGIIIVACCIGTWFCNHIATSHIALKVTKQ