Protein Info for ABI39_RS14015 in Phocaeicola dorei CL03T12C01

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 transmembrane" amino acids 21 to 38 (18 residues), see Phobius details amino acids 50 to 75 (26 residues), see Phobius details amino acids 95 to 118 (24 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 237 to 261 (25 residues), see Phobius details amino acids 274 to 297 (24 residues), see Phobius details amino acids 318 to 339 (22 residues), see Phobius details amino acids 359 to 380 (22 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details amino acids 418 to 438 (21 residues), see Phobius details PF01554: MatE" amino acids 24 to 185 (162 residues), 87.2 bits, see alignment E=9.9e-29 amino acids 249 to 403 (155 residues), 87.6 bits, see alignment E=7.6e-29 TIGR00797: MATE efflux family protein" amino acids 24 to 419 (396 residues), 203.3 bits, see alignment E=3.1e-64 PF14667: Polysacc_synt_C" amino acids 139 to 281 (143 residues), 36.3 bits, see alignment E=6.1e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_2744)

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>ABI39_RS14015 MATE family efflux transporter (Phocaeicola dorei CL03T12C01)
MKENNPHILGTEKVGKLLLEYSIPAIIGMTLTSLYNIIDSVFIGHGVGAMAISGLAISFP
LMNLLVAFCTLVGVGGATISSIRLGQKDTDGAEKVLGNVTVLCVINSIFYGGITLLFLDQ
ILFFFGASHDTLPYARDFMQIILIGSPVTYVMIGLNNIMRATGYPRKAMLSSMLTVGCNI
ILAPVFIFWLGWGIRGAATATILSQFAGMIWVLSHFMQEKSYIRFKKGIFKLRKRIVENI
FSIGMSPFLMNVCASAIVIIFNKSLLLYGGDLAIGAYGILNRLLMLFVMVIMGLTMGMQP
IVGYNHGAHKFGRVKQTLKYCMIAGGCITSLGFVFSELFPNLVVNMFTDDKELTALARTG
LQIGVLMFPFVGIQIVISSFFQSIGKAKISIFLSLSRQLLYLLPCLLLLPHWWGLNGIWL
SMPVSDLLAFITACLMLAHHIKKLNKITEV