Protein Info for ABI39_RS13830 in Phocaeicola dorei CL03T12C01

Annotation: L-lactate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 54 to 79 (26 residues), see Phobius details amino acids 105 to 134 (30 residues), see Phobius details amino acids 143 to 165 (23 residues), see Phobius details amino acids 176 to 198 (23 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details amino acids 236 to 254 (19 residues), see Phobius details amino acids 274 to 294 (21 residues), see Phobius details amino acids 323 to 343 (21 residues), see Phobius details amino acids 364 to 391 (28 residues), see Phobius details amino acids 397 to 415 (19 residues), see Phobius details amino acids 480 to 498 (19 residues), see Phobius details TIGR00795: transporter, lactate permease (LctP) family" amino acids 1 to 497 (497 residues), 396.4 bits, see alignment E=1.1e-122 PF02652: Lactate_perm" amino acids 2 to 497 (496 residues), 419.6 bits, see alignment E=2.1e-129 PF03553: Na_H_antiporter" amino acids 236 to 498 (263 residues), 27.1 bits, see alignment E=2.5e-10

Best Hits

KEGG orthology group: K03303, lactate transporter, LctP family (inferred from 99% identity to bvu:BVU_2711)

Predicted SEED Role

"L-lactate permease" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (499 amino acids)

>ABI39_RS13830 L-lactate permease (Phocaeicola dorei CL03T12C01)
MNLVLAIIPVLLLIILMAFFKMSGDKSSVISLVVTMLIAFFGFHFPVDDLLFSFLYGALK
AVSPILIIILMAIFSYNVLLKTEKMEIIKQQFSSISTDKSIQVLLLTWGFGGLLEAMAGF
GTAVAIPAAILISLGFKPVFSATVSLIANSVATAFGAIGTPVLVLAKETNLDVLVLSANV
VLQLSVLMFLIPFVLLFLTNSKLKSLPKNIFLSLLVGGVSLGSQYIAARYMGAESPAIIG
SILSIIVIVAYGKLTASKEEKARKSTLKGLEVLNAWSIYLLILFLIILTSPLFPGLRTTL
ENNWVTRISLPINDSTMNYTVSWLTHAGVLLFVGTFVGGLIQGAKIWELFAVLWNTVKQL
KKTFITVICLVSLSTIMDTAGMISVIATALAVATGSLYPLFAPVIGCLGTFITGSDTSSN
ILFGKLQANVAGHIQVSPDWLSAANTVGATGGKIISPQSIAIATSAGNQQGKEGEILKSA
IPYALAYVVITGVIVYIFS