Protein Info for ABI39_RS10355 in Phocaeicola dorei CL03T12C01

Annotation: Gfo/Idh/MocA family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF01408: GFO_IDH_MocA" amino acids 68 to 192 (125 residues), 54.5 bits, see alignment E=1.9e-18 PF21252: Glyco_hydro_109_C" amino acids 204 to 354 (151 residues), 128.6 bits, see alignment E=1.8e-41

Best Hits

Swiss-Prot: 99% identical to G1095_BACV8: Glycosyl hydrolase family 109 protein 5 (BVU_2041) from Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

KEGG orthology group: None (inferred from 99% identity to bvu:BVU_2041)

Predicted SEED Role

"Oxidoreductase, Gfo/Idh/MocA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>ABI39_RS10355 Gfo/Idh/MocA family oxidoreductase (Phocaeicola dorei CL03T12C01)
MRTFKSLMISLCMGTTLCMCLPQTTTAQTVSSGDSWKWDKGTIVIDTPERPSGQKSVLGL
TIPKMEVVRVGFVGLGMRGPGAVERFTYIPGTQIVALCDYEASRAEKCQDILKKASMPKA
AIYSGEKGYEELCKRTDIDLVYIAADWLHHFPVAKCALENGKNVAIEVPSAMNLQECWDL
INLSEKTRKHCMILENCCYDWFEMNTLNMAQQGVFGEIIRAQGAYIHNLSPFWDHYWKNG
KEDKLGWRLDYNMKHRGDVYATHGLGPVAQALDIHRGDRITTLVAMDTKSVVGKDLVEKR
TGEECKEFRNGDHTTTLLRTANGKVIEIQHNVMTPQPYNRLYQLTGSKGFANKYPVEGYA
LDAAQLTASGVQPKVDDLNSHGFLPQAEMEALIEKYQHPILKKYGEMAKEVGGHGGMDFI
MDSRLVYCLQNGLPLDMDVYDLAEWCCLAELGAISMDNGCAAVAFPDFTRGEWNVTKGYK
HAYASPEDENASMEKAKAFTAKLKEQGAKEWAKEAKKKRNK