Protein Info for ABI39_RS08505 in Phocaeicola dorei CL03T12C01

Annotation: NADH-quinone oxidoreductase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L
  • amino acids 4 to 630 (627 residues), 559.9 bits, E=5.3e-172
• PF00662: Proton_antipo_N
  • amino acids 73 to 124 (52 residues), 70.4 bits, 9.7e-24
• PF00361: Proton_antipo_M
  • amino acids 140 to 432 (293 residues), 258 bits, E=1.1e-80

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 98% identity to bvu:BVU_1752)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• aerobic respiration III (alternative oxidase pathway) (2/3 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
• aerobic respiration I (cytochrome c) (2/4 steps found)
• NAD(P)/NADPH interconversion (2/6 steps found)
• Fe(II) oxidation (1/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Protein Sequence (633 amino acids)

>ABI39_RS08505 NADH-quinone oxidoreductase subunit L (Phocaeicola dorei CL03T12C01)
MEHTILILILPFLSFLILGLAGMRMKNGLAGAIGTVSLAGVALLSYLTAFNYFAGGRTAE
GVYPTLTPYNFEWLPFTTNLHIDMGIMLDPISVMMLVVISTVSLMVHIYSFGYMKGEKGF
QRYYAFLSLFTMSMLGLVVATNIFQMYVFWELVGVSSYLLIGFYYTKKEAIAASKKAFIV
TRFADLGFLIGILIYGYYAETFSFTPQLQVLAVAGSMIPLALGLMFIGGAGKSAMFPLHI
WLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIGYAPEVLHWIAYIGAFTAFYAAS
VACAQSDIKRVLAFSTISQIGFMIVALGVCTSMNPHEGGLGYMASMFHLFTHAMFKALLF
LGAGCIIHAVHSNEMSAMGGLHKYMPVTHWTFLIACLAISGIWPFSGFFSKDEILTACFQ
FSPVIGWIMTGIAAMTAFYMFRLYYCIFWNGEWKGHSHESGLGAHTPHEAPLTMTFPLMF
LAAITCVAGFIPFGNLISSNGEAYTIHLDMQIAATSIIIAIASIALATWMYAGKKQPVAN
YLAHTFPRLHTAAYHRFYMDEIWLFVTKKIIFRCISTPIAWWDRHVIDQFFNFTAWSTHA
TADEIRDMQSGNVQQYSIWFLAGALILTLILLI