Protein Info for ABI39_RS08500 in Phocaeicola dorei CL03T12C01

Annotation: NADH-quinone oxidoreductase subunit M

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 50 (21 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 113 to 131 (19 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 210 to 229 (20 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 273 to 295 (23 residues), see Phobius details amino acids 302 to 322 (21 residues), see Phobius details amino acids 330 to 351 (22 residues), see Phobius details amino acids 371 to 390 (20 residues), see Phobius details amino acids 409 to 433 (25 residues), see Phobius details amino acids 457 to 476 (20 residues), see Phobius details TIGR01972: proton-translocating NADH-quinone oxidoreductase, chain M" amino acids 4 to 490 (487 residues), 421.5 bits, see alignment E=2.2e-130 PF00361: Proton_antipo_M" amino acids 130 to 416 (287 residues), 226.6 bits, see alignment E=2.1e-71

Best Hits

Swiss-Prot: 36% identical to NU4C_ANGEV: NAD(P)H-quinone oxidoreductase chain 4, chloroplastic (ndhD) from Angiopteris evecta

KEGG orthology group: K00342, NADH dehydrogenase I subunit M [EC: 1.6.5.3] (inferred from 100% identity to bvu:BVU_1751)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (493 amino acids)

>ABI39_RS08500 NADH-quinone oxidoreductase subunit M (Phocaeicola dorei CL03T12C01)
MNILSFFIIVPLLMLASLWASRSINQVRGVMVVGSSILLALSVYLTIDYIELRQAGATGE
MLFTASTVWYAPLHICYSVGVDGISVAMLLLSSIIVFTGTFASWKLQPLTKEYFMWFTLL
SVGVFGFFVSTDLFTMFMFYEVALIPMYLLIGVWGSGRKEYAAMKLTLMLMGGSAFLLIG
ILGIFYGAGGETMNLLEIAKLHIPHEMQRIFFPLIFLGFGVLGALFPFHTWSPDGHASAP
TAVSMLHAGVLMKLGGYGCFRVAMYLMPEGAAMWGDVFLILTTISVVYGAFSAVVQTDLK
YINAYSSVSHCGLVLFALLMMTRTSCTGAILQMLSHGLMTALFFALIGMIYGRTHTRDVR
LMGGLMKIMPFLAVGYVIAGLANLGLPGLSGFVAEMTVFVGSFQNDDTFHRVCTLVATTS
IVITAVYILRVVGKILYGKVLNPEHLKLTDATWDERVAVICLIACVAGLGLAPFWISDLI
SNSVEPIISQLLN