Protein Info for ABI39_RS08095 in Phocaeicola dorei CL03T12C01

Annotation: fumarylacetoacetate hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF01557: FAA_hydrolase" amino acids 2 to 188 (187 residues), 167.5 bits, see alignment E=1.8e-53

Best Hits

Swiss-Prot: 41% identical to Y643_PYRHO: Uncharacterized protein PH0643 (PH0643) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

KEGG orthology group: None (inferred from 98% identity to bvu:BVU_1638)

Predicted SEED Role

"Fumarylacetoacetate hydrolase family protein" in subsystem Gentisare degradation or Salicylate and gentisate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>ABI39_RS08095 fumarylacetoacetate hydrolase family protein (Phocaeicola dorei CL03T12C01)
MKIIAVGMNYVAHCHELHADENLPEEPVIFMKPDSALLKDSKPFFIPDFSQQVDYETELV
VRINRLGKNIAPRFASRYYDAVTVGIDFTARDLQRQFREEGKPWELCKGFDSSAAIGDFV
SVDRFKDIQNLNFHLDIDGKTVQRGNTADMLFKVDEIIAYVSRFFTLKIGDLLYTGTPVG
VGPVSIGQHLQGYLEGEKLLDFYVR