Protein Info for ABI39_RS06970 in Phocaeicola dorei CL03T12C01

Annotation: TIGR04133 family radical SAM/SPASM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 TIGR04133: radical SAM enzyme, rSAM/lipoprotein system" amino acids 9 to 358 (350 residues), 617.7 bits, see alignment E=5.2e-190 PF04055: Radical_SAM" amino acids 38 to 197 (160 residues), 75.8 bits, see alignment E=4.6e-25 TIGR04085: radical SAM additional 4Fe4S-binding SPASM domain" amino acids 269 to 343 (75 residues), 37.1 bits, see alignment E=3.4e-13 PF13186: SPASM" amino acids 269 to 330 (62 residues), 30.9 bits, see alignment E=2.8e-11

Best Hits

KEGG orthology group: None (inferred from 70% identity to bsa:Bacsa_1642)

Predicted SEED Role

"putative heme biosynthesis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>ABI39_RS06970 TIGR04133 family radical SAM/SPASM protein (Phocaeicola dorei CL03T12C01)
MNINAPLSIRRRMGLEIFRRLENERTEEHQLKQLFWECTLRCNLHCRHCGSDCKKIAGHP
DMPKEDFLRVLDSVSAQNDPHKIFVIITGGEPLMRKDLEECGRAIYERGFPWGMVTNGLY
MTRERLNGLLDAGLHTATVSLDGFATDHNWMRGNPQSFERAVEAIKLMVQVPDFVFDVVT
CVNKHSYMRLEELKDFLISLGVKGWRLFTIFPVGRAAKDPELQLSNEEFRGVMEFIRKSR
KEGRIHVSYGCEGFLGNYEAEVRDTFFACRAGISVGSVLIDGAISACPSIRADYHQGNIY
ENDFMEVWNHRFKPYRDREWMKKDECADCKYFRFCKGNGMHLRDENGDLLFCHLKRLQTP