Protein Info for ABI39_RS05095 in Phocaeicola dorei CL03T12C01

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 842 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF17900: Peptidase_M1_N" amino acids 61 to 209 (149 residues), 53.1 bits, see alignment E=4.5e-18 PF01433: Peptidase_M1" amino acids 251 to 462 (212 residues), 162.8 bits, see alignment E=9.5e-52

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 96% identity to bvu:BVU_1274)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (842 amino acids)

>ABI39_RS05095 aminopeptidase N (Phocaeicola dorei CL03T12C01)
MKTYIGYLIVMCNLLLCSCQQTTSNPRFYDEGVSQELAILRKQEIKELKYKLYFSIPEQK
SVPVNGEIAIEFNLDAPQEIILDFREKPEKIKSVSVNGQTARYEFHNEHIILPEKNIVEG
KNNITIKFIAGNQSLNRNDEFLYTLLVPDRARTLFPCFEQPNLKATFSLRLDIPTAWKAV
SNTYITKEETKGNCKTVTFAPTEPLSTYLFSFVTGKLEHQEYTEGNRKISAYYRETDSKK
VAQLDTIFKQVTASLNWLEEYTNVPYPFAKYDFIILPGFQYGGMEHTGATLYNDTQMFLS
ENPTPDEELRRTQLIAHETAHMWFGDLVTMNWFDDVWTKEVFANYFAALITEPLFPQVNH
QLNWMKTYTAASLSEDRTPGTTAIRQPLDNLQNAGLIDGQIIYNKAPVMMVKLVELMGKE
AFREGIQEYLKTYAYANATWDDLIQILNSKTEQDLTAFSDVWVNQKGMPIINFEVSGKQQ
TIHQQDPYQRGLNWPQKFNITLCGTRDTTIEASLTDSLCRITLPFTPTRILPNTDGRGYG
LFIPDNNSLHWLLEHWQEIDNETTRQAVLMMMHENYQAKRIPNTTWMNALLNGIHCEKNP
LIASTLTNYLSSPLQETSSVERDKIENELYRLSYSHPIPSCRIQLLRLLITEAASPAMIQ
CLYSLWETERVQQLNEKDYTTLAYELALRIPEQGKEILKTQRQRIHNPDRLRQFDFISRA
MTADTLKLDSLFQSLLQAENRRIEPWAATTLSYLNHSTRKDYAVKYIRPALEELTEVQRT
GDIFFPRNWVGALLRNHDSEAAYKAVETFLSVYPDYSPLLKNKILQAAYPLYRKYADKEK
IS