Protein Info for ABI39_RS04810 in Phocaeicola dorei CL03T12C01

Annotation: HAMP domain-containing histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 transmembrane" amino acids 35 to 55 (21 residues), see Phobius details amino acids 251 to 274 (24 residues), see Phobius details PF00512: HisKA" amino acids 282 to 346 (65 residues), 42.9 bits, see alignment E=4.2e-15 PF02518: HATPase_c" amino acids 395 to 511 (117 residues), 90.2 bits, see alignment E=1.2e-29

Best Hits

KEGG orthology group: None (inferred from 95% identity to bvu:BVU_1314)

Predicted SEED Role

"Two-component system sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>ABI39_RS04810 HAMP domain-containing histidine kinase (Phocaeicola dorei CL03T12C01)
MCYRRLMKSYLVLSKEREYLFCAYFCQTMKIPFKAIAALIILSLIGVFAYQAYWLTGLYT
SMKKDMDNCLIETLQVSDYNEMMERCDSVKRSNETINGYIESSINLDSSALITKVIETEP
FKQQKRFGLEINEPVSTTIDKNGTLELLTKYFQRGIHSQLDLFTEINLHTFDSLFTRTLA
MRGIIYLPHRIEIVNLRQDSTIVQGLSSPQKYRPGKEAVSYYYNYDLYNKMAYRLWVEPT
NTIVLQQMKGILYTSFFIIIILGLSFWFLIRIILRQKSVEEMKEDFTHNITHELKTPIAV
AYAANDALLNFNGAENLTKRQNYLQIIQAQLKQLSGLVEQILSMSMEQRKNFRLNYEPVE
LRPMLENLISQHRLKADKPTEFKLIMKEDMILRADRLHLYNVISNLIDNAIKYSDEKAYI
CISATRCNGSCNSSCNAHVTLKIQDKGIGIPTDKQKHLFNKFYRVPTGNLHNVKGYGLGL
YYVKTMIEQHKGTVSVESITGKGSTFTLQIPE