Protein Info for ABI39_RS02675 in Phocaeicola dorei CL03T12C01

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1344 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 784 to 805 (22 residues), see Phobius details amino acids 1301 to 1324 (24 residues), see Phobius details PF07494: Reg_prop" amino acids 36 to 58 (23 residues), 19.1 bits, see alignment (E = 4.2e-07) amino acids 217 to 240 (24 residues), 22.7 bits, see alignment (E = 2.9e-08) amino acids 319 to 341 (23 residues), 16.7 bits, see alignment (E = 2.7e-06) amino acids 412 to 432 (21 residues), 16.2 bits, see alignment (E = 3.8e-06) amino acids 496 to 518 (23 residues), 17.6 bits, see alignment (E = 1.3e-06) amino acids 584 to 607 (24 residues), 21.7 bits, see alignment (E = 6.1e-08) PF07495: Y_Y_Y" amino acids 716 to 779 (64 residues), 55.7 bits, see alignment 1.5e-18 PF00512: HisKA" amino acids 835 to 899 (65 residues), 46.2 bits, see alignment 1.5e-15 PF02518: HATPase_c" amino acids 947 to 1056 (110 residues), 85.4 bits, see alignment E=1.6e-27 PF00072: Response_reg" amino acids 1094 to 1204 (111 residues), 91.2 bits, see alignment E=2e-29 PF12833: HTH_18" amino acids 1263 to 1341 (79 residues), 67.2 bits, see alignment 5.4e-22 PF00165: HTH_AraC" amino acids 1306 to 1340 (35 residues), 32.8 bits, see alignment (E = 2.3e-11)

Best Hits

KEGG orthology group: None (inferred from 78% identity to bvu:BVU_0512)

Predicted SEED Role

"Two-component system sensor histidine kinase/response regulator, hybrid"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1344 amino acids)

>ABI39_RS02675 response regulator (Phocaeicola dorei CL03T12C01)
MKHTYSFSISLLLSFIYLFHASAQPYVIKRLGVEDGMSSNYVVSVTQDKKGYLWIATESG
LNRFDGRQFNIYTKNNSGLSGNELNVVLADPYENKVWIGTQRDGLCYFDYETETISRIPA
TGNYMLSNDITDLSVAADSGLWITHYHFGVDYYDRKTKLFTPYSSKNVKGLEGNNWVSKE
DGNGNLYIGHHLRGLSIVSLKDRTAKNYQHDPNNPYSIPDNEVRALCIDKNKNVWVGTNN
GLALFNPQSEKFITFKHIEGNENSLLSDQILDIKQMKDGTLWICTNMGGVSILNLRENTF
ISPEKITFSNITVTNDNHGLSGPNARSIIQDSFGNIWIGNYRGGVDFISYAQPLFNTIAY
TIEKQGKINNKQVWGLWADNHQIWLGGEGELGIYEKGKKTKNFSLHECRLHPQTHINVIY
QDKQERLWLGTYKNGILLYTPKDGRITRIGDKDSEFLDICSFSEDINGKIWIGTQTGIYS
YFNNQLSYEKELNAQLPDIMVHGIIRDKNGKLWVGTFGKGVCVFDEDDKKLYNFTTDHSF
PSNAVNYMMEDSRKRILVATREGIIIFKDVSQPNIFVSFGAKEGLENTQVRAIQEDHDGY
IWISTNGGISRLDEKNKRFYNYNYHDGIPMGDFMDGSTCITPDGTLFFGSQNGACYFNPR
ELSSPREVSPVTITQFFIYNKQTESRDTRLPVPISNRIVELPYNQNTFNISFNVLDYTQS
SQVEFSYMLEGLENAWYSTQGDNQVTFRNIPHGNYVFKVKTRFRNQEWNENAAQLTVVIA
PPLWLTWYAKLSYVILFIFALYALLRFYKRKLDLESSLEVERKQSLNKQELNEERLRFYT
NITHELRTPLTLILGPLEDLLSDATLSPKHANKISIIHDSATRLLNLINRILEFRKTETQ
NRKLSVAKGDLGQLVQEVGLRYKELNPNNKVNYHIHIETEDTEIFYDADMITIILDNLMS
NAAKYTSEGDITLSLRSVEENQIKYTEISVSDTGHGIDAEALPHIFDRYYQAKSKYQASG
SGIGLALVKGLSELHEGILKVESAVDTGTTFTLRLLTENTYPNAIHAQHDMEKKPMDAEE
TTITDTPTENHPIVLVVEDNADIREYIRSSFTDIYEVITAKDGKEGWELAQARIPNIIVS
DIMMPVMDGIELCKRIKEDMRTSHIPVILLTAKDSLQDKEEGYASGADSYLTKPFSAKLL
HSRINNLLETRKKIASLLALTDTQPKQESAVSSLNKLDNEFLQKITQIIEENLEMEKMDI
AFIADKMCMSHSTLYRKIKGLTDMSANEFIRKVKMRKGVELLMSGQYTISEIAYMIGFSS
VAYFRQCFKDEYGMSPSDYVKQKQ