Protein Info for ABI39_RS01880 in Phocaeicola dorei CL03T12C01

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 57 to 81 (25 residues), see Phobius details amino acids 97 to 122 (26 residues), see Phobius details amino acids 136 to 157 (22 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 194 to 215 (22 residues), see Phobius details amino acids 242 to 267 (26 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 322 to 343 (22 residues), see Phobius details amino acids 362 to 385 (24 residues), see Phobius details amino acids 396 to 416 (21 residues), see Phobius details amino acids 422 to 442 (21 residues), see Phobius details PF01554: MatE" amino acids 22 to 183 (162 residues), 63.7 bits, see alignment E=1.7e-21 amino acids 256 to 408 (153 residues), 60.7 bits, see alignment E=1.4e-20 PF14667: Polysacc_synt_C" amino acids 137 to 220 (84 residues), 37.7 bits, see alignment E=2.2e-13

Best Hits

KEGG orthology group: None (inferred from 98% identity to bvu:BVU_0343)

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>ABI39_RS01880 MATE family efflux transporter (Phocaeicola dorei CL03T12C01)
MKDSIDFGSMEIPKLFRKLLIPTVLGMVFSAVFVITDGIFVGQGIGSDALAAVNITAPLF
LISTGIGLMFGVGASVVASIHLSQGKLKAARINVTQAVVVSSLFLAVLWGVVCLFAPQVA
VWLGSSERLLPLAVEYMYWFLPFLVFSALLSSGMFFVRLDGSPNYAMLCNAIPAVVNILL
DYVFIFIFKWGMMGAALATSLGYILGAGMIVVYLSRRKNVIHFCRVKLSKKSMRLTWRNV
RYMCHLGASTFLCEAAIACMMFAGNYVFIHYLGEDGVAAFSIACYFFPIIFMVYNAIGQS
AQPILSYNFGAGDAMRVRSAFRLALGTAVTCGLVFFALTALFNHQIVAMFIDRSYPAYDI
AVAGLPLFASGFIFFAVNIVSIGYFQSVERARPAMMITVLRGFVFMVLCLFGLPLLLKVP
GIWLAVPLAEILTFLVIMAIYYRKHQWVRR