Protein Info for ABI39_RS01435 in Phocaeicola dorei CL03T12C01

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 transmembrane" amino acids 19 to 39 (21 residues), see Phobius details amino acids 43 to 44 (2 residues), see Phobius details amino acids 51 to 83 (33 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 139 to 160 (22 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 238 to 262 (25 residues), see Phobius details amino acids 274 to 295 (22 residues), see Phobius details amino acids 318 to 339 (22 residues), see Phobius details amino acids 358 to 379 (22 residues), see Phobius details amino acids 392 to 413 (22 residues), see Phobius details amino acids 419 to 439 (21 residues), see Phobius details PF01554: MatE" amino acids 25 to 186 (162 residues), 97.7 bits, see alignment E=6e-32 amino acids 252 to 401 (150 residues), 71.6 bits, see alignment E=6.4e-24 TIGR00797: MATE efflux family protein" amino acids 25 to 420 (396 residues), 192 bits, see alignment E=7.8e-61 PF14667: Polysacc_synt_C" amino acids 140 to 294 (155 residues), 35.4 bits, see alignment E=1.1e-12

Best Hits

KEGG orthology group: None (inferred from 98% identity to bvu:BVU_0273)

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (456 amino acids)

>ABI39_RS01435 MATE family efflux transporter (Phocaeicola dorei CL03T12C01)
MAKTGTPTELGTQPIGKLLLQYAIPAIIAMTASSLYNMVDSIFIGHGVGPLAISGLAITF
PLMNLAAAFGSLVGVGASTLVSVKLGQKDYATAQNILGNVVTLNFIIGIGFSILTLLFLD
PILYFFGASPDTISYARDYMVIILLGNVITHMYLGLNALLRASGHPQKAMIATITTVIIN
TILDPIFIYLFHWGIQGAAIATILAQIIALVWQFKTFTNKNELLHLHRGIYKLRGTIVKN
TIAIGMSPFLMNLAACFIVIFINKGLKEYDGDLAIGAFGIVNRIVFLFVMIVMGLNQGMQ
PIAGYNFGAQQYHRVNQVLKLTIYGATTVTTTGFLVGELMPELAVSAFTTHEGLIQLSAT
GLRIVVIFFPIIGFQMVTSNFFQSIGMAGKAIFLSLTRQLLFLLPCIILLPLFWGSAGIW
WSMPISDLAASIVAGVMLYRQFKIFNTHGNKLKVEN