Protein Info for A4249_RS15645 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: potassium-transporting ATPase subunit KdpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 transmembrane" amino acids 46 to 67 (22 residues), see Phobius details amino acids 73 to 92 (20 residues), see Phobius details amino acids 229 to 254 (26 residues), see Phobius details amino acids 263 to 286 (24 residues), see Phobius details amino acids 593 to 611 (19 residues), see Phobius details amino acids 622 to 642 (21 residues), see Phobius details amino acids 661 to 683 (23 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 25 to 682 (658 residues), 959.8 bits, see alignment E=6.6e-293 TIGR01494: HAD ATPase, P-type, family IC" amino acids 82 to 350 (269 residues), 93.6 bits, see alignment E=9.8e-31 amino acids 381 to 608 (228 residues), 145.5 bits, see alignment E=1.8e-46 PF00122: E1-E2_ATPase" amino acids 117 to 293 (177 residues), 91.1 bits, see alignment E=6.5e-30 PF00702: Hydrolase" amino acids 310 to 536 (227 residues), 88.3 bits, see alignment E=9e-29

Best Hits

Swiss-Prot: 83% identical to KDPB_CAUVC: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 87% identity to bsb:Bresu_3241)

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0H2 at UniProt or InterPro

Protein Sequence (688 amino acids)

>A4249_RS15645 potassium-transporting ATPase subunit KdpB (Brevundimonas sp. GW460-12-10-14-LB2)
MTQVTLDPREGGRASPLAGGLSGQMIGRAVGDAFVKLNPVKLINNPVIFTTWIVALLSTL
SAAAAIASGQSAGFAVQLALWLWATVLFANVAESIAEGRGKAAADSLRATRVTTKAKLIV
DPKTGSVVPTNASELEVGSIILVEAGDVIASDGEIVEGVASVNEAAITGESAPVIRESGG
DRSAVTGGTTVVSDWIKVRITAKPGSTFLDRMIAMVEGADRRKTPNELALAVLLAGLTLI
FLIAVVTLVGLGAYSGVDLDPMVLGALFITLIPTTIGGLLSAVGIAGMDRLLKVNVLATS
GRAVEAAGDVDTLLLDKTGTITFGNRMATEVIPVPGVRPEAALAAAVMASLADETPEGRS
IVELGRNAGVSVDQPAGAVAIPFTAVTRQSGLDVGKDSWRKGAVDAVLKDLNLTDGSAPA
EFRQAVDRIARSGGTPLAVTQNGVLVGVIHLKDVVKPGVKARFADLRRMGLRTVMITGDN
PVTAAAIASEAGVDDYLAEATPEDKMRLIKAEQAKGRLVAMCGDGANDAPALAQADVGVA
MQTGAQAAREAGNMVDLDSDPTKVIEIVEVGKQLLITRGALTTFSVANDVAKYFAIIPAM
FVVALPSLGALNVMRLHSPESAILSAVIFNALVIVALIPLALKGVKYRAIGAGALLGRNL
LIYGLGGLIAPFVGIKLIDLLISGLGLA