Protein Info for A4249_RS14980 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: TetR/AcrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF00440: TetR_N" amino acids 16 to 61 (46 residues), 49.7 bits, see alignment 2.5e-17 PF14246: TetR_C_7" amino acids 82 to 195 (114 residues), 70 bits, see alignment E=1.8e-23

Best Hits

KEGG orthology group: None (inferred from 60% identity to bsb:Bresu_0416)

Predicted SEED Role

"transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NSR4 at UniProt or InterPro

Protein Sequence (205 amino acids)

>A4249_RS14980 TetR/AcrR family transcriptional regulator (Brevundimonas sp. GW460-12-10-14-LB2)
MARRRGQVDERKSEAILDAAATLFADKGLQAKMDEIAKLAGVSKQTVYNRFASKLEIAQA
LASKRVEDIVAPLRGAGDPQTVLEALALTLLNRVCSGDKVGSMRGVALVSVEAPDIAHAI
YEAGPRRSLRELGAWLAEQTRLGRMNVADPEEAAEMFAGLVLGHGHLRAMLDVPQLEADK
RAGRAREAARIFMAAHPPATAAKTS