Protein Info for A4249_RS14875 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: benzoate/H(+) symporter BenE family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 47 to 67 (21 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 99 to 118 (20 residues), see Phobius details amino acids 125 to 143 (19 residues), see Phobius details amino acids 152 to 169 (18 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 216 to 239 (24 residues), see Phobius details amino acids 251 to 274 (24 residues), see Phobius details amino acids 293 to 317 (25 residues), see Phobius details amino acids 323 to 343 (21 residues), see Phobius details amino acids 361 to 386 (26 residues), see Phobius details TIGR00843: benzoate transporter" amino acids 7 to 383 (377 residues), 269.4 bits, see alignment E=2.5e-84 PF03594: BenE" amino acids 13 to 383 (371 residues), 344.7 bits, see alignment E=3.2e-107

Best Hits

KEGG orthology group: K05782, benzoate membrane transport protein (inferred from 56% identity to gau:GAU_3673)

Predicted SEED Role

"Benzoate transport protein" in subsystem Benzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A168NSJ1 at UniProt or InterPro

Protein Sequence (394 amino acids)

>A4249_RS14875 benzoate/H(+) symporter BenE family transporter (Brevundimonas sp. GW460-12-10-14-LB2)
MTAPAFSMRALPASAFSSAAMATVIGFGGTVALVVQAGQALGADAGQIGSMVTALCLGIG
APGALLSWRLKIPVVLAWSTPAAALLAASTLGLSWPTAIGAFIFAALLMILTGLIPALGR
LAARIPAAVASAMLAGVLLPFVLRLFKVVPDETALVVGLIAVFLIFRRLWPTWALPAVLA
AAFVVLAMRGQLALPAGTDLFGHLEPVAPVFDWKAAVSLGFPLFLVTLAAQNLPGLVVLQ
SAGYPPPANRLILSTGVASLLIAPFGGHGVNLAAITAAICTGPDAHPDVAKRWIVGVIYG
GLYLVVALFAAPLAGLFIAMPPAVLAAVTGLALIAPLTGALQNMMMDVGSRESAVLTFAA
TASGLTLFGVGSAFWGLAVGFAALAAMRWIRPTA