Protein Info for A4249_RS14735 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details TIGR03725: tRNA threonylcarbamoyl adenosine modification protein YeaZ" amino acids 3 to 207 (205 residues), 172.8 bits, see alignment E=4.9e-55 PF00814: TsaD" amino acids 32 to 124 (93 residues), 94.4 bits, see alignment E=5.1e-31

Best Hits

KEGG orthology group: None (inferred from 54% identity to cse:Cseg_0015)

Predicted SEED Role

"TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I1G9 at UniProt or InterPro

Protein Sequence (226 amino acids)

>A4249_RS14735 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB (Brevundimonas sp. GW460-12-10-14-LB2)
MRLLVIDTALGACTAAVFEDDRALAMRFEPMTKGHQERIGGLVRDVMAEAGGGFDSLDRI
GVTVGPGSFTGLRVGLAFAQGLGAALDRPVVGLSALDALAASLANQDGPIAALIDARRGQ
VYARLFADGGPLGPDEALSLEQAGRRIADIGSGVALVGNGAAVVTQAFPDLTFAHLDDRV
APSPEALARLAAAADPTTHPPRPLYLRAPDATPPSRLPGQPRQPAP