Protein Info for A4249_RS14685 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: M28 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF04389: Peptidase_M28" amino acids 303 to 512 (210 residues), 142.9 bits, see alignment E=5.2e-46

Best Hits

KEGG orthology group: None (inferred from 47% identity to npp:PP1Y_AT17407)

Predicted SEED Role

"Peptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I1W6 at UniProt or InterPro

Protein Sequence (548 amino acids)

>A4249_RS14685 M28 family metallopeptidase (Brevundimonas sp. GW460-12-10-14-LB2)
MRHALPAVSILALMMACSPALAQETTPNIDAARMNESVRVLASDDFEGRAPASAGEEKTV
AWLVEQFKAAGAEGGGPDGAFVQVAHLSRTRQDGPATVVATVGGKTISLERGPDVLVSSD
RPTNHITVTDAPVVFVGYGATAPERQWDDFKNMDVRGKVIVVLVNDPDFQAPDGDPVAGK
FDGNAMTFYGRWTYKFQEAGRRGAAGVLVVHETAGAGYPWSTLQNSSAAPKFDIVRANPD
AERAAFQGWIQRAKVEELFTAVGLDFAALKDSARSADFKPVVLPGLTMSVDFGQIADKVE
TKNVIARIPGSERPDETVMYGAHWDGYGVGTPNAQGDKIYNAAVDNATGVAALLELAHAF
ADGPHAKRSVVFAAWSGEEAGLLGSTYYAANPVWPLETTVANINVDSLLPGAEIDPNVVV
IGKGKNQLDDILARHATETGRTLIADPAPQAGAFYRSDHFPLALKGVPALFPAAGFTGAS
AASRDYVQNRYHQPTDEWDSTWTMDAAAADVALIYAVGRELADGDQWPEWNAGAEFGPAR
DTSKASRR