Protein Info for A4249_RS14315 in Brevundimonas sp. GW460-12-10-14-LB2
Annotation: ShlB/FhaC/HecB family hemolysin secretion/activation protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 47% identity to pzu:PHZ_c2209)Predicted SEED Role
No annotation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A160I2A9 at UniProt or InterPro
Protein Sequence (508 amino acids)
>A4249_RS14315 ShlB/FhaC/HecB family hemolysin secretion/activation protein (Brevundimonas sp. GW460-12-10-14-LB2) MAVAGPVRADAEPASTPDAGCAGCLILTSMLIQGVSAYPLADLADTYDQQLARRVSVDDL VQSANAITARYRNDGYFLTRAVVAETDPAIGAARIVVFEGYISELKLTGDGARAVEPILK PLVNQRPLTIGELDRRLSLASDVPGVKLTSRIEPIIGDPAQHRLVVETAMTSGSAGVYVD NRGSETQGPWQVYLSGARNSTFMAGDQITLGVLTVPDRPDELTYIDASYSVVASGGGRVR FGVSGYETDAPLQNASGWVGGSSRMASVTLSHPLVRSRDKNLWLNAGLDVRRVEQNYVAT GRTDETLTVARMSVAGQRRSSSGWMAGSIQLSKGIDAFGATTERSPLNTRYDATGEFFKV NAQVSAYRDLSKYVGVYVEASGQWSDDALLSSEEFFVGGPTYGRAYDYGEASGDKAVAGM IEARVGYDPKGDFITFAQAFAFFDTAKVWNKTPGRDWSEQLTSAGVGSRITFDRKATLRI EFAKPLSRAPYNQPDKGWRTFVSLSKQF