Protein Info for A4249_RS13950 in Brevundimonas sp. GW460-12-10-14-LB2
Annotation: 2-polyprenylphenol 6-hydroxylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K03688, ubiquinone biosynthesis protein (inferred from 74% identity to bsb:Bresu_0044)Predicted SEED Role
"Ubiquinone biosynthesis monooxygenase UbiB" in subsystem Ubiquinone Biosynthesis
MetaCyc Pathways
- superpathway of ubiquinol-8 biosynthesis (early decarboxylation) (7/12 steps found)
- ubiquinol-8 biosynthesis (early decarboxylation) (4/8 steps found)
- superpathway of chorismate metabolism (37/59 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A160HZS4 at UniProt or InterPro
Protein Sequence (526 amino acids)
>A4249_RS13950 2-polyprenylphenol 6-hydroxylase (Brevundimonas sp. GW460-12-10-14-LB2) MGDLTSRIYRTAPPPPATVAVQNPVASFLRLLGWLWVLARHDALIPREVTHLLPAWTRPF ARFVQLFSGRAGRQGRPGQRLGKAFEHLGPVAIKLGQVLATRADIFGLEFARDLGRLKDA LPPFSLEEARREIEKSLGRPAESLFIDLSPPVAAASLAQAHRATLADGRAVAVKVLRPGV ERRVANGLDSMRLAARLVWRLVPMARRLEPSAFVETIANSLDLELDMRLEAAAASEMAEV LAKDGYMSAPAVIWDGVGKRVLTLEWAQGVPMTDPALLDLPGLDKDQLADNVVRAFLVQA LDHGVFHADLHEGNLFASAPAHLTAIDFGIVGRLGPAERRYLAEILWGFISRDYDRISRV HFEAGYVPPHHSVETFAQALRAVGEPVIGRAASQVSMGRLLGQLFEITALFDMRLRPELI LLQKTMVSVEGVARRLQPDHDLWKAAQPVVERWIRRELGPQAQARDAINEMIAAARAISR LVQEPPRPAAVVIEKSGTPAWVTASVTVAVIAALAALGLSLWPYLT