Protein Info for A4249_RS13480 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: protein-export chaperone SecB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 170 PF02556: SecB" amino acids 22 to 159 (138 residues), 156.7 bits, see alignment E=1.8e-50 TIGR00809: protein-export chaperone SecB" amino acids 24 to 158 (135 residues), 127.8 bits, see alignment E=1.5e-41

Best Hits

Swiss-Prot: 63% identical to SECB_CAUSK: Protein-export protein SecB (secB) from Caulobacter sp. (strain K31)

KEGG orthology group: K03071, preprotein translocase subunit SecB (inferred from 73% identity to bsb:Bresu_0356)

Predicted SEED Role

"Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160HZF9 at UniProt or InterPro

Protein Sequence (170 amino acids)

>A4249_RS13480 protein-export chaperone SecB (Brevundimonas sp. GW460-12-10-14-LB2)
MTDAAPPAEQPQQGDAQQGQPAGPGFRILAQYVRDFSFENPRAPESLRIDGKPAIDLGVE
MAAQGRPDGLFELDLKLSIKATHENQPVFHVELVYGGLFQLANVQEQDIEPLLLIECPRY
LFPFAREIISGATADGGFYPPFQLDPIDFAAIYIARQQQIAQQPVETGQA