Protein Info for A4249_RS13280 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: prolyl oligopeptidase family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 724 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF02897: Peptidase_S9_N" amino acids 43 to 448 (406 residues), 142.1 bits, see alignment E=2.3e-45 PF00326: Peptidase_S9" amino acids 515 to 717 (203 residues), 147.8 bits, see alignment E=3.3e-47

Best Hits

KEGG orthology group: K01322, prolyl oligopeptidase [EC: 3.4.21.26] (inferred from 77% identity to bsb:Bresu_0455)

Predicted SEED Role

"Prolyl endopeptidase (EC 3.4.21.26)" (EC 3.4.21.26)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.26

Use Curated BLAST to search for 3.4.21.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I1F3 at UniProt or InterPro

Protein Sequence (724 amino acids)

>A4249_RS13280 prolyl oligopeptidase family serine peptidase (Brevundimonas sp. GW460-12-10-14-LB2)
MIRASAVALATLLASTSLTSVSMAQTPASSPAPASGGFATSDATDPYLWLEEVEGERAME
WVKAHNERTFAVLQGDPHYETLHQQALEIVQAQDRIPSPGFTHDGHIDNFWQDAQHVRGL
WRRTTLDSYRTATPEWQTILDIDALAAAEGQNWVYKGSTCLQPEERYCLISLSNGGKDAV
TLREFDTVERKFVDGGITLPESKGGASWIDKDTLMISRDFGPGTLTNSGYPMVVKRMKRG
QTPDQAETLFTGQPTDVSVSGYTLRDADGVVKATLINRSVDFYSSETWRLGDDGALTQLQ
LPAKSDITGLVQGQLLVSLKQDWTAPSGQDFKTGDLIAWPLEAWLADQATPAQLVLRPTE
RQAIEGVNVTRNRLVVALYDNVRGAVRVYTPGQGEWAHTTLDLPQNVSVGVGSASEKDDK
VFVSVTGYLNPSSLWLADAATGAVDQVKSMPAKFDAAGMTVDQHEARSADGTMIPYFVVH
KADMPLDGSNPTLLYGYGGFESSLLPGYSATVGKLWLERGGVYVIANTRGGGEFGPRWHE
AALQQNRQRAHEDFQAVALDLIARDITSQPKLGIMGGSQGGLFMGAMLTQRPDLINAAVI
QVPLFDMLRFHKLLAGASWIGEYGNPDIPEQRAWIQQYSPYQNLRAGQPYPEVFIHTSTK
DDRVHPGHARKAAARLEELGYPVLFYENVDGGHAAGANLRETARRLALEYTYLSRRLMDT
PAQE