Protein Info for A4249_RS13270 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: DUF1223 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF06764: DUF1223" amino acids 46 to 237 (192 residues), 181.5 bits, see alignment E=1.1e-57

Best Hits

KEGG orthology group: None (inferred from 59% identity to bsb:Bresu_0453)

Predicted SEED Role

"hypothetical protein that often co-occurs with aconitase" in subsystem TCA Cycle

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I0X8 at UniProt or InterPro

Protein Sequence (251 amino acids)

>A4249_RS13270 DUF1223 domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MNTKGWIIAGTVMAGALMSVASAAQPAAGRPPLAPRHATANGPPVVVELFTAQGCGGCIE
ANAAVEKAAAQPGVIALTYGVDYWDYLGWTDTFARPEFVQRQRAYRAALRQRGVSTPQVV
IDGRRQVSGARSVELETAIDQEAVRQAWPPEIEFRENGAGVGVGSGRAPVGGAEVVAVTY
TPGPQVVEVRQGENRGQAVRHMNVVRGVTRLGEWRGRPMLYALPSARPGEAVAVLVQGKT
DKRILGAAVRD