Protein Info for A4249_RS13230 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: ubiquitin-activating E1 FCCH domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 636 transmembrane" amino acids 29 to 49 (21 residues), see Phobius details PF13400: Tad" amino acids 28 to 74 (47 residues), 38.7 bits, see alignment 1.5e-13 PF16190: E1_FCCH" amino acids 256 to 327 (72 residues), 35.2 bits, see alignment E=1.6e-12

Best Hits

Predicted SEED Role

"FIG00483747: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I1G5 at UniProt or InterPro

Protein Sequence (636 amino acids)

>A4249_RS13230 ubiquitin-activating E1 FCCH domain-containing protein (Brevundimonas sp. GW460-12-10-14-LB2)
MVKVSNRIGRAVKALRTFTSRLSSDRGGNVVMIFALVMPALIMLTLGGIDINRVTTAKAR
VQDALDAAALAAARSSYTDPKDLKTVALVALRANLRNASVEPFADDAVKIELTKDQIVIA
DIQVQVKTLIANVVLPPYGKILDDTLPVSVHSEVNRSSKDIEVSLVLDITGSMASNNRIG
DLKNAANQLIKLVVQPASKQTPYYSRMSIVPYSIGVNLGTRADAARGASIGSTSISGAAW
AAAAAKSISGITRASPGVVTANGHGLSTDDYVWISGVSGMTQINNRAYKVVRIDANRVSL
QYQSGQNWYALNTSSGYSSYSSGGQIRKCMRSDCFVTITSVNHGLSEDEGVQITGVNGMT
ALNNSSGLFEVYERTSKDAFVVPVGGATYADYSNGGAVQCGRDGCAKRVFRDPQYNRLNV
FDNTTCVSERAGSSAYTDTAPGSAYVGRNYASPRNPCPAAIIQPLTSNIDTLTSLVNGLS
VTGSTAGQIGLGWGWYTVSNQFNGLWSSNPAAAYAPTKVLKAVILMTDGEFNTPYCGGVI
ARDAGSGSGNLYDKIACDATNGDPFDQAAKLCTGMKAKGVIVYTVGFSITPGSDAANILS
TCATDKDKAFLPQSGADLSNDFQAIGRDITRLRISR