Protein Info for A4249_RS13170 in Brevundimonas sp. GW460-12-10-14-LB2

Annotation: potassium transporter Kup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 658 transmembrane" amino acids 43 to 64 (22 residues), see Phobius details amino acids 81 to 104 (24 residues), see Phobius details amino acids 133 to 157 (25 residues), see Phobius details amino acids 174 to 193 (20 residues), see Phobius details amino acids 204 to 225 (22 residues), see Phobius details amino acids 247 to 269 (23 residues), see Phobius details amino acids 281 to 302 (22 residues), see Phobius details amino acids 322 to 347 (26 residues), see Phobius details amino acids 373 to 394 (22 residues), see Phobius details amino acids 400 to 421 (22 residues), see Phobius details amino acids 430 to 452 (23 residues), see Phobius details amino acids 459 to 477 (19 residues), see Phobius details PF02705: K_trans" amino acids 48 to 580 (533 residues), 700.8 bits, see alignment E=5.8e-215

Best Hits

Swiss-Prot: 58% identical to KUP2_BRADU: Probable potassium transport system protein kup 2 (kup2) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 86% identity to bsb:Bresu_0501)

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A160I1G0 at UniProt or InterPro

Protein Sequence (658 amino acids)

>A4249_RS13170 potassium transporter Kup (Brevundimonas sp. GW460-12-10-14-LB2)
MAGDTPHDASAPSPASNTPDKPTHATGPESHIPGGQAAKHGGFWALTIGAIGVVFGDIGT
SPLYALREAIDHARSGVGGDLAVIGVVSLAFWALMVVVTFKYVFFLMRADNKGEGGTLSL
MALAQFAVGRRSAWIFILGVCGAALFYGDGIITPAISVLSAVEGLQDAPGLAGRLDSFIV
PISAGILIALFLVQSRGTASLAKYFGPITAVWFLSLGALGLYHIFDDVSVLRALSPHYGV
MLLLNDGFLGFVILGSVFLAVTGAEALYADMGHFGKAPIRMGWLAFVLPCLTLNYLGQGA
LILDNPAASENPFWNMVPQFAYWPMLILATAATVIASQAVITGAFSVTQQAVQLGLLPRI
DIKNTSETQAGQIFVPAVNTFLMVGVLVLLVVFQSSHNLTAAYGVAVTGTMLVNTLMAYS
VIRKGWKWPMWAVAGTLIPFAFIDSVFLTSNLLKIPDGAWMPLVLGALLVVVMWTWVRGT
QILTAKTRKDSLPLNDLIEMLQARPPHRAPGMAIFLTSDPDVAPVALMHNLKHNKVLHEK
NVILTVRTSERPRVKEADRVRMEPINDDFKKVTVTYGFMETPNVPRALGLCRKQGLKFDI
MSTSFFLGRRSLIPSARQGMPLWQDKLFIFLMRNAANPTDFFHIPPGRVVELGAQVAV