Protein Info for A4249_RS13160 in Brevundimonas sp. GW460-12-10-14-LB2
Annotation: ribulose-phosphate 3-epimerase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 53% identical to RPEC_CUPNH: Ribulose-phosphate 3-epimerase, chromosomal (cbbEC) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
KEGG orthology group: K01783, ribulose-phosphate 3-epimerase [EC: 5.1.3.1] (inferred from 83% identity to bsb:Bresu_0282)MetaCyc: 53% identical to ribulose-phosphate 3-epimerase (Escherichia coli K-12 substr. MG1655)
Ribulose-phosphate 3-epimerase. [EC: 5.1.3.1]
Predicted SEED Role
"Ribulose-phosphate 3-epimerase (EC 5.1.3.1)" in subsystem Calvin-Benson cycle or Conserved gene cluster associated with Met-tRNA formyltransferase or Pentose phosphate pathway or Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization (EC 5.1.3.1)
MetaCyc Pathways
- pentose phosphate pathway (non-oxidative branch) I (5/5 steps found)
- formaldehyde assimilation III (dihydroxyacetone cycle) (10/12 steps found)
- pentose phosphate pathway (7/8 steps found)
- Bifidobacterium shunt (12/15 steps found)
- pentose phosphate pathway (partial) (3/3 steps found)
- Rubisco shunt (8/10 steps found)
- pentose phosphate pathway (non-oxidative branch) II (5/6 steps found)
- Calvin-Benson-Bassham cycle (10/13 steps found)
- ethene biosynthesis V (engineered) (18/25 steps found)
- superpathway of glucose and xylose degradation (12/17 steps found)
- formaldehyde assimilation II (assimilatory RuMP Cycle) (6/9 steps found)
- photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (18/26 steps found)
- heterolactic fermentation (12/18 steps found)
- oxygenic photosynthesis (11/17 steps found)
- 1-butanol autotrophic biosynthesis (engineered) (18/27 steps found)
KEGG Metabolic Maps
- Carbon fixation in photosynthetic organisms
- Pentose and glucuronate interconversions
- Pentose phosphate pathway
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.1.3.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A161IX20 at UniProt or InterPro
Protein Sequence (221 amino acids)
>A4249_RS13160 ribulose-phosphate 3-epimerase (Brevundimonas sp. GW460-12-10-14-LB2) MAVTPLICPSILASDFARLGEEVRALEAAGADWIHVDVMDGHFVPNLTLGPDIVKAIRPH TTLPFDVHLMVAPVDPWLEAFREAGADVLTVHPESGPHLHRTLGRIRQLGAKAGVVFNPA TPLSILEEVVDLVDLVLIMSVNPGFGGQKFIDSSLKKIAGARAILDRAGSSAHLQVDGGV TSANAGACVAAGADALVAGSFVFKGDYATNIAALKAAPAVS